Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis (Q73073993)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

title

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Sebastian Wesselborg

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

author name string

Engels IH

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Stepczynska A

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Stroh C

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Lauber K

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Berg C

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Schwenzer R

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Jänicke RU

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Porter AG

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Belka C

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Gregor M

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Schulze-Osthoff K

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

language of work or name

English

0 references

publication date

1 September 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

issue

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

page(s)

4563-4573

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11030145%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203824

1 November 2019

exact match

0 references

cites work

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

The tyrosine kinase lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

1 reference

7 January 2021

Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Oncogene-dependent apoptosis is mediated by caspase-9.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Differential regulation and ATP requirement for caspase-8 and caspase-3 activation during CD95- and anticancer drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

CASH, a novel caspase homologue with death effector domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

E1B 19,000-molecular-weight protein interacts with and inhibits CED-4-dependent, FLICE-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Inhibition of Fas-induced apoptosis by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

An induced proximity model for caspase-8 activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Apoptosis signaling by death receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c rel

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Death by a thousand cuts: an ever increasing list of caspase substrates

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

The CD95/CD95 ligand system is not the major effector in anticancer drug-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Dominant-negative FADD inhibits TNFR60-, Fas/Apo1- and TRAIL-R/Apo2-mediated cell death but not gene induction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203824

7 January 2021