Modulation of the IL-10/IL-12 cytokine circuit by interferon-beta inhibits the development of epitope spreading and disease progression in murine autoimmune encephalomyelitis (Q73153718)

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scientific article published on 01 November 2000

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English	Modulation of the IL-10/IL-12 cytokine circuit by interferon-beta inhibits the development of epitope spreading and disease progression in murine autoimmune encephalomyelitis	scientific article published on 01 November 2000

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scholarly article

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1 November 2019

Modulation of the IL-10/IL-12 cytokine circuit by interferon-beta inhibits the development of epitope spreading and disease progression in murine autoimmune encephalomyelitis (English)

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1 November 2019

author name string

V K Tuohy

1

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1 November 2019

M Yu

2

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1 November 2019

L Yin

3

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1 November 2019

P M Mathisen

4

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1 November 2019

J M Johnson

5

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1 November 2019

J A Kawczak

6

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1 November 2019

publication date

1 November 2000

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1 November 2019

Journal of Neuroimmunology

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1 November 2019

111

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1 November 2019

1-2

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1 November 2019

55-63

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11063821%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Functional diversity of helper T lymphocytes

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Interferon in experimental autoimmune encephalomyelitis (EAE): effects of exogeneous interferon on the antigen-enhanced adoptive transfer of EAE

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Immunologic therapy of multiple sclerosis

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Interferons: pleiotropic cellular modulators

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7 January 2021

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Interferon alpha increases the frequency of interferon gamma-producing human CD4+ T cells

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7 January 2021

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VLA-4 expression on peripheral blood lymphocytes is downregulated after treatment of multiple sclerosis with interferon beta

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7 January 2021

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Reduction of transendothelial migration of mononuclear cells in interferon-beta1b-treated multiple sclerosis patients

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7 January 2021

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Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection

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7 January 2021

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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

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7 January 2021

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The molecular cell biology of interferon-gamma and its receptor

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7 January 2021

based on heuristic

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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A phase III trial of intramuscular recombinant interferon beta as treatment for exacerbating-remitting multiple sclerosis: design and conduct of study and baseline characteristics of patients. Multiple Sclerosis Collaborative Research Group (MSCRG).

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7 January 2021

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Interferon beta in multiple sclerosis: is IL-12 suppression the key?

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7 January 2021

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High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

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Interferon production by individual cells in culture

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7 January 2021

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Determinant spreading and the dynamics of the autoimmune T-cell repertoire.

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Interferon beta-1b inhibits gelatinase secretion and in vitro migration of human T cells: a possible mechanism for treatment efficacy in multiple sclerosis

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7 January 2021

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Functional responses and costimulator dependence of memory CD4+ T cells.

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7 January 2021

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Interferon (IFN) beta acts downstream of IFN-gamma-induced class II transactivator messenger RNA accumulation to block major histocompatibility complex class II gene expression and requires the 48-kD DNA-binding protein, ISGF3-gamma

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7 January 2021

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Polyinosinic acid: polycytidylic acid promotes T helper type 1-specific immune responses by stimulating macrophage production of interferon-alpha and interleukin-12

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7 January 2021

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Immunological aspects of demyelinating diseases

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7 January 2021

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Human recombinant interferon-beta influences T helper subset differentiation by regulating cytokine secretion pattern and expression of homing receptors

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7 January 2021

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IFN-beta differentially regulates CD40-induced cytokine secretion by human dendritic cells

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7 January 2021

based on heuristic

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Interferon beta decreases T cell activation and interferon gamma production in multiple sclerosis

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7 January 2021

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Immunomodulatory effects of interferon-beta-1b in vivo: induction of the expression of transforming growth factor-beta1 and its receptor type II

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T cell response to myelin basic protein before and after treatment with interferon beta in multiple sclerosis

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Influence of interferon beta-1a dose frequency on PBMC cytokine secretion and biological effect markers

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Interferon beta induces interleukin-10 expression: relevance to multiple sclerosis

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An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

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Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system

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Interferon beta-1b decreases the migration of T lymphocytes in vitro: effects on matrix metalloproteinase-9.

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Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group

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Immunobiology of interleukin-12.

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The epitope spreading cascade during progression of experimental autoimmune encephalomyelitis and multiple sclerosis

1 reference

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7 January 2021

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Epitope spreading

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Interferon beta modulates experimental autoimmune encephalomyelitis by altering the pattern of cytokine secretion

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Interferon-beta inhibits progression of relapsing-remitting experimental autoimmune encephalomyelitis.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0165-5728(00)00384-2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11063821%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11063821%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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