Distribution of a 20-mer phosphorothioate oligonucleotide, CGP69846A (ISIS 5132), into airway leukocytes and epithelial cells following intratracheal delivery to brown-norway rats (Q73163241)

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scientific article published on 01 October 1999

Language	Label	Description	Also known as
English	Distribution of a 20-mer phosphorothioate oligonucleotide, CGP69846A (ISIS 5132), into airway leukocytes and epithelial cells following intratracheal delivery to brown-norway rats	scientific article published on 01 October 1999

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scholarly article

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1 November 2019

Distribution of a 20-mer phosphorothioate oligonucleotide, CGP69846A (ISIS 5132), into airway leukocytes and epithelial cells following intratracheal delivery to brown-norway rats (English)

1 reference

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1 November 2019

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H Danahay

1

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1 November 2019

J Giddings

2

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1 November 2019

R A Christian

3

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1 November 2019

H E Moser

4

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1 November 2019

J A Phillips

5

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publication date

1 October 1999

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1 November 2019

Pharmaceutical Research

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1 November 2019

16

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1 November 2019

10

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1 November 2019

1542-1549

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Lung epithelial cell (A549) interaction with unopsonized environmental particulates: quantitation of particle-specific binding and IL-8 production

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Effect of TNF-alpha antisense oligomers on cytokine production by primary murine alveolar macrophages.

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Co-administration of polyanions with a phosphorothioate oligodeoxynucleotide (CGP 69846A): a role for the scavenger receptor in its in vivo disposition

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Respirable antisense oligonucleotides as novel therapeutic agents for asthma and other pulmonary diseases.

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Cellular distribution of phosphorothioate oligodeoxynucleotides in normal rodent tissues

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Quantitation of phosphorothioate oligonucleotides in human plasma

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Pharmacokinetic properties of several novel oligonucleotide analogs in mice

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Specific suppression of human tumor necrosis factor-alpha synthesis by antisense oligodeoxynucleotides

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Tritium labeling of antisense oligonucleotides by exchange with tritiated water

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Spontaneous and cationic lipid-mediated uptake of antisense oligonucleotides in human monocytes and lymphocytes

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Expression of the acetyl low density lipoprotein receptor by rabbit fibroblasts and smooth muscle cells. Up-regulation by phorbol esters.

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Pulmonary bioavailability of a phosphorothioate oligonucleotide (CGP 64128A): comparison with other delivery routes

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Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells

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A placebo-controlled trial of ICAM-1 antisense oligonucleotide in the treatment of Crohn's disease.

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Pharmacokinetics, metabolism, and elimination of a 20-mer phosphorothioate oligodeoxynucleotide (CGP 69846A) after intravenous and subcutaneous administration

1 reference

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Lung macrophage uptake of unopsonized environmental particulates. Role of scavenger-type receptors

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Identifiers

10.1023/A:1015048419558

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Europe PubMed Central

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1 November 2019

1 reference

Europe PubMed Central

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1 November 2019

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