Sequence-dependent growth inhibition and DNA damage formation by the irinotecan-5-fluorouracil combination in human colon carcinoma cell lines (Q73446707)

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scientific article published on 01 December 1999

Language	Label	Description	Also known as
English	Sequence-dependent growth inhibition and DNA damage formation by the irinotecan-5-fluorouracil combination in human colon carcinoma cell lines	scientific article published on 01 December 1999

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scholarly article

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Sequence-dependent growth inhibition and DNA damage formation by the irinotecan-5-fluorouracil combination in human colon carcinoma cell lines (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

colon carcinoma

1 reference

based on heuristic

inferred from title

Gilberto Schwartsmann

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

D R Mans

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

I Grivicich

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

G J Peters

3

1 reference

Europe PubMed Central

PubMed publication ID

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4 November 2019

publication date

1 December 1999

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

European Journal of Cancer

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

35

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

13

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1851-1861

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Clinical highlights from the National Cancer Data Base: 1996.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Fluorouracil: biochemistry and pharmacology

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical relevance of biochemical modulation of 5-fluorouracil

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced Colorectal Cancer Meta-Analysis Project

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

ZD1694 (Tomudex): A new thymidylate synthase inhibitor with activity in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

CPT-11 in human colon-cancer cell lines and xenografts: characterization of cellular sensitivity determinants

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. CPT-11 Gastrointestinal Cancer Study Group.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy of CPT-11 (irinotecan) as a single agent in metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase II trial of irinotecan in patients with metastatic colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Simultaneous administration of CPT-11 and fluorouracil: alteration of the pharmacokinetics of CPT-11 and SN-38 in patients with advanced colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase I clinical and pharmacokinetic study of irinotecan, fluorouracil, and leucovorin in patients with advanced solid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

CPT-11 (irinotecan) and 5-fluorouracil: a promising combination for therapy of colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A phase II study of irinotecan alternated with five days bolus of 5-fluorouracil and leucovorin in first-line chemotherapy of metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phase I study of a weekly schedule of irinotecan, high-dose leucovorin, and infusional fluorouracil as first-line chemotherapy in patients with advanced colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular interactions of 5-fluorouracil and the camptothecin analogue CPT-11 (irinotecan) in a human colorectal carcinoma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of CPT-11 in combination with other anti-cancer agents in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Combination of irinotecan (CPT11) and 5-fluorouracil with an analysis of cellular determinants of drug activity

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Thymidylate synthase from untreated human colorectal cancer and colonic mucosa: Enzyme activity and inhibition by 5-fluoro-2′-deoxyuridine-5′-monophosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

45 Carboxylesterases-amidases

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical mechanisms of interferon modulation of 5-fluorouracil activity in colon cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The reconstitution of higher-order DNA structure after X-irradiation of mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Formation of different reaction products with single- and double-stranded DNA by the ortho-quinone and the semi-quinone free radical of etoposide (VP-16-213).

1 reference

https://api.crossref.org/works/10.1016%2FS0959-8049%2899%2900222-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0959-8049(99)00222-1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674003%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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