Evidence that translocation of the proteinase precedes its acylation in the serpin inhibition pathway (Q73643075)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10753871%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Evidence that translocation of the proteinase precedes its acylation in the serpin inhibition pathway (English)

1 reference

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5 November 2019

author name string

P Mellet

series ordinal

1

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5 November 2019

J G Bieth

series ordinal

2

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5 November 2019

language of work or name

English

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publication date

1 April 2000

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Journal of Biological Chemistry

5 November 2019

published in

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5 November 2019

volume

275

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5 November 2019

issue

15

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5 November 2019

page(s)

10788-10795

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Cross-class inhibition of the cysteine proteinases cathepsins K, L, and S by the serpin squamous cell carcinoma antigen 1: a kinetic analysis

5 November 2019

cites work

1 reference

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Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation.

21 January 2018

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Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

21 January 2018

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Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

21 January 2018

1 reference

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The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

21 January 2018

1 reference

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An ester bond linking a fragment of a serine proteinase to its serpin inhibitor.

21 January 2018

1 reference

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Stopped flow fluorescence energy transfer measurement of the rate constants describing the reversible formation and the irreversible rearrangement of the elastase-alpha1-proteinase inhibitor complex

21 January 2018

1 reference

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Structural insights into serpin-protease complexes reveal the inhibitory mechanism of serpins

21 January 2018

1 reference

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Mapping the serpin-proteinase complex using single cysteine variants of alpha1-proteinase inhibitor Pittsburgh

21 January 2018

1 reference

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Formation of the covalent serpin-proteinase complex involves translocation of the proteinase by more than 70 A and full insertion of the reactive center loop into beta-sheet A.

21 January 2018

1 reference

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The anticoagulant activation of antithrombin by heparin

21 January 2018

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Mapping the heparin-binding site of mucus proteinase inhibitor

21 January 2018

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The biostructural pathology of the serpins: critical function of sheet opening mechanism

21 January 2018

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Kinetic mechanism of the inhibition of cathepsin G by alpha 1-antichymotrypsin and alpha 1-proteinase inhibitor

21 January 2018

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21 January 2018

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Kinetics of the inhibition of human pancreatic elastase by recombinant eglin c. Influence of elastin

21 January 2018

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Mechanism of action of naturally occurring proteinase inhibitors. Studies with anhydrotrypsin and anhydrochymotrypsin purified by affinity chromatography

21 January 2018

1 reference

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Pig pancreatic anhydro-elastase. Role of the serine-195 hydroxy group in the binding of inhibitors and substrate

21 January 2018

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Evidence for the extent of insertion of the active site loop of intact alpha 1 proteinase inhibitor in beta-sheet A

21 January 2018

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Accelerated conversion of human plasminogen activator inhibitor-1 to its latent form by antibody binding

21 January 2018

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Diverse effects of pH on the inhibition of human chymase by serpins

21 January 2018

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Inhibitory mechanism of serpins: loop insertion forces acylation of plasminogen activator by plasminogen activator inhibitor-1

21 January 2018

1 reference

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Antichymotrypsin interaction with chymotrypsin. Reactions following encounter complex formation

21 January 2018

1 reference

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Inhibitory mechanism of serpins. Identification of steps involving the active-site serine residue of the protease

21 January 2018

1 reference

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Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase

21 January 2018

1 reference

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Major proteinase movement upon stable serpin-proteinase complex formation

21 January 2018

1 reference

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Change in environment of the P1 side chain upon progression from the Michaelis complex to the covalent serpin-proteinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.10788

On the interaction of inhibitor and proteases Evidence for the formation of a covalent crosslinkage and non-covalent weak bondings between the inhibitor and proteases

21 January 2018

1 reference

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Serpin-serine protease binding kinetics: alpha 2-antiplasmin as a model inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.15.10788

21 January 2018

Identifiers

DOI

10.1074/JBC.275.15.10788

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10753871%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference