Coupling of oral human or porcine insulin to the B subunit of cholera toxin (CTB) overcomes critical antigenic differences for prevention of type I diabetes (Q73943062)

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scientific article published on 01 October 2003

Language	Label	Description	Also known as
English	Coupling of oral human or porcine insulin to the B subunit of cholera toxin (CTB) overcomes critical antigenic differences for prevention of type I diabetes	scientific article published on 01 October 2003

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scholarly article

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8 November 2019

Coupling of oral human or porcine insulin to the B subunit of cholera toxin (CTB) overcomes critical antigenic differences for prevention of type I diabetes (English)

1 reference

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8 November 2019

1 reference

based on heuristic

inferred from title

type-1 diabetes

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based on heuristic

inferred from title

4

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8 November 2019

author name string

J S Petersen

1

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8 November 2019

S Bregenholt

2

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8 November 2019

V Apostolopolous

3

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8 November 2019

T Wolfe

5

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8 November 2019

A Hughes

6

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8 November 2019

K De Jongh

7

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8 November 2019

M Wang

8

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8 November 2019

T Dyrberg

9

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8 November 2019

M G Von Herrath

10

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8 November 2019

publication date

1 October 2003

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8 November 2019

Clinical and Experimental Immunology

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8 November 2019

134

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8 November 2019

1

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8 November 2019

38-45

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8 November 2019

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Predictive medicine in autoimmune diseases: from the identification of genetic predisposition and environmental influence to precocious immunotherapy

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Antigen-specific mediated suppression of beta cell autoimmunity by plasmid DNA vaccination

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Complexities in the treatment of autoimmune disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Antigen-specific therapy for autoimmune disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of anti-self (virus) immune response

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Pathological changes in the islet milieu precede infiltration of islets and destruction of beta-cells by autoreactive lymphocytes in a transgenic model of virus-induced IDDM.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Neither B lymphocytes nor antibodies directed against self antigens of the islets of Langerhans are required for development of virus-induced autoimmune diabetes.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

A peptide-binding motif for I-A(g7), the class II major histocompatibility complex (MHC) molecule of NOD and Biozzi AB/H mice

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Oral tolerance for the treatment of autoimmune diseases

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Oral insulin administration and residual beta-cell function in recent-onset type 1 diabetes: a multicentre randomised controlled trial. Diabète Insuline Orale group.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

No effect of oral insulin on residual beta-cell function in recent-onset type I diabetes (the IMDIAB VII). IMDIAB Group.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Protective DNA vaccination against organ-specific autoimmunity is highly specific and discriminates between single amino acid substitutions in the peptide autoantigen

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Oral tolerance in the treatment of inflammatory autoimmune diseases

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

The role of clonal deletion and anergy in oral tolerance

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Tolerance induction with agonist peptides recognized by autoaggressive lymphocytes is transient: therapeutic potential for type 1 diabetes is limited and depends on time-point of administration, choice of epitope and adjuvant

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Induction of Autoimmune Diabetes by Oral Administration of Autoantigen

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

T helper cell differentiation in multiple sclerosis and autoimmunity

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2003.02255.X

21 January 2018

Coexpression of B7-1 and viral ("self") transgenes in pancreatic beta cells can break peripheral ignorance and lead to spontaneous autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral tolerance to insulin and the insulin B-chain: cell lines and cytokine patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral insulin treatment suppresses virus-induced antigen-specific destruction of beta cells and prevents autoimmune diabetes in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Application of oral tolerance to the treatment of autoimmune diseases--active suppression and bystander suppression]

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for an underlying CD4 helper and CD8 T-cell defect in B-cell-deficient mice: failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from muMT/muMT mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A plant-based cholera toxin B subunit-insulin fusion protein protects against the development of autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA immunization to prevent autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin in oral immune "tolerance": a one-amino acid change in the B chain makes the difference

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin B-chain reactive CD4+ regulatory T-cells induced by oral insulin treatment protect from type 1 diabetes by blocking the cytokine secretion and pancreatic infiltration of diabetogenic effector T-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral administration of cholera toxin B-insulin conjugates protects NOD mice from autoimmune diabetes by inducing CD4+ regulatory T-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoreactive CD4+ T cells protect from autoimmune diabetes via bystander suppression using the IL-4/Stat6 pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral tolerance, an active immunologic process mediated by multiple mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predicting insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural analysis of peptides capable of binding to more than one Ia antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel approach to the generation of high affinity class II-binding peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen-specific immunotherapy: is it a real possibility to combat T-cell-mediated autoimmunity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral tolerance in humans. T cell but not B cell tolerance after antigen feeding

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholera toxin B subunit as transmucosal carrier-delivery and immunomodulating system for induction of antiinfectious and antipathological immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12974752

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2249.2003.02255.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12974752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12974752%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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