Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis (Q74449037)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis (English)

1 reference

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10 November 2019

1 reference

Zhang Y

1

1 reference

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10 November 2019

Fujita N

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Tsuruo T

series ordinal

3

1 reference

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10 November 2019

language of work or name

English

0 references

publication date

1 February 1999

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10 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

18

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10 November 2019

issue

5

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10 November 2019

page(s)

1131-1138

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Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors

10 November 2019

cites work

1 reference

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7 January 2021

Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1

1 reference

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7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

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7 January 2021

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

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7 January 2021

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

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7 January 2021

Activation-induced T-cell death is cell cycle dependent and regulated by cyclin B.

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7 January 2021

Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases

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7 January 2021

Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

Inhibition of cyclin-dependent kinases by p21

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7 January 2021

Cell cycle and apoptosis: common pathways to life and death.

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7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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7 January 2021

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

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7 January 2021

Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.

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7 January 2021

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

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7 January 2021

Protease activation during apoptosis: death by a thousand cuts?

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7 January 2021

Aspartate-based inhibitor of interleukin-1 beta-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells

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7 January 2021

Actin cleavage by CPP-32/apopain during the development of apoptosis

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7 January 2021

Apoptosis and the cell cycle.

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7 January 2021

Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

Principles of CDK regulation

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7 January 2021

The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition

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7 January 2021

Caspases: killer proteases

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7 January 2021

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

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7 January 2021

The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells

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7 January 2021

Genetic determinants of p53-induced apoptosis and growth arrest

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7 January 2021

A model for p53-induced apoptosis

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7 January 2021

Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c

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7 January 2021

Premature p34cdc2 activation required for apoptosis.

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7 January 2021

Substrate specificities of caspase family proteases

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7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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7 January 2021

Caspases and caspase inhibitors

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7 January 2021

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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7 January 2021

Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.

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7 January 2021

p21 is a universal inhibitor of cyclin kinases

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7 January 2021

Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

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7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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7 January 2021