Three-dimensional representations of G protein-coupled receptor structures and mechanisms (Q74818940)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

title

Three-dimensional representations of G protein-coupled receptor structures and mechanisms (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

13 November 2019

main subject

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

author name string

Irache Visiers

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

Juan A Ballesteros

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

publication date

1 January 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

published in

Methods in Enzymology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

volume

343

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

page(s)

329-371

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000.

13 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Receptors and G proteins as primary components of transmembrane signal transduction. Part 1. G-protein-coupled receptors: structure and function.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

GPCRDB: an information system for G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Molecular tinkering of G protein-coupled receptors: an evolutionary success

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Crystal structure of rhodopsin: A G protein-coupled receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Advances in comparative protein-structure modelling

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Analysis of insertions/deletions in protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Structural probing of a microdomain in the dopamine transporter by engineering of artificial Zn2+ binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Structure and function of receptors coupled to G proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

New alignment strategy for transmembrane proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

A simple method for displaying the hydropathic character of a protein

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Geometry of proline-containing alpha-helices in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Prokink: a protocol for numerical evaluation of helix distortions by proline.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Proline residues in transmembrane helices: structural or dynamic role?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The fourth transmembrane segment of the dopamine D2 receptor: accessibility in the binding-site crevice and position in the transmembrane bundle

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Influence of proline residues on protein conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Proline for alanine substitutions in the C-peptide helix of ribonuclease A.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

An analysis of the periodicity of conserved residues in sequence alignments of G-protein coupled receptors. Implications for the three-dimensional structure

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The prediction and orientation of α-helices from sequence alignments: the combined use of environment-dependent substitution tables, Fourier transform methods and helix capping rules

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The bacterial photosynthetic reaction center as a model for membrane proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Predicting the point at which transmembrane helices protrude from the bilayer: a model of the antenna complexes from photosynthetic bacteria.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Hinges, swivels and switches: the role of prolines in signalling via transmembrane alpha-helices

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Modeling of transmembrane seven helix bundles

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

X-ray structure of bacteriorhodopsin at 2.5 angstroms from microcrystals grown in lipidic cubic phases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Analysis and refinement of criteria for predicting the structure and relative orientations of transmembranal helical domains

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Principles that determine the structure of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Evolution of protein cores. Constraints in point mutations as observed in globin tertiary structures.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Environment-specific amino acid substitution tables: tertiary templates and prediction of protein folds

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Structure-derived substitution matrices for alignment of distantly related sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Amino acid substitution matrices

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

A 3D-1D substitution matrix for protein fold recognition that includes predicted secondary structure of the sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Molecular characterization of a functional cDNA encoding the serotonin 1c receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The guanine nucleotide regulatory protein-coupled receptors for nucleosides, nucleotides, amino acids and amine neurotransmitters

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Adrenergic receptors as models for G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Conformational changes of cytosolic loops of bovine rhodopsin during the transition to metarhodopsin-II: an investigation by Fourier transform infrared difference spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Structure and function in rhodopsin. Cysteines 65 and 316 are in proximity in a rhodopsin mutant as indicated by disulfide formation and interactions between attached spin labels

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Automated method for modeling seven-helix transmembrane receptors from experimental data

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Combined biophysical and biochemical information confirms arrangement of transmembrane helices visible from the three-dimensional map of frog rhodopsin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The transmembrane 7-alpha-bundle of rhodopsin: distance geometry calculations with hydrogen bonding constraints

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Low resolution structure of bovine rhodopsin determined by electron cryo-microscopy.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Arrangement of rhodopsin transmembrane α-helices

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Opioid receptor three-dimensional structures from distance geometry calculations with hydrogen bonding constraints

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

On the spatial disposition of the fifth transmembrane helix and the structural integrity of the transmembrane binding site in the opioid and ORL1 G protein-coupled receptor family

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

3D modeling, ligand binding and activation studies of the cloned mouse delta, mu; and kappa opioid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Novel mixed mode Monte Carlo/stochastic dynamics simulations of the complex between TRH and TRH receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Construction of a 3D model of the cannabinoid CB1 receptor: determination of helix ends and helix orientation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Functional Microdomains in G-protein-coupled Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The agonist SR 146131 and the antagonist SR 27897 occupy different sites on the human CCK(1) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

What makes red visual pigments red? A resonance Raman microprobe study of retinal chromophore structure in iodopsin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The arrangement of the transmembrane helices in the secretin receptor family of G-protein-coupled receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The relation between the divergence of sequence and structure in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Challenges at the frontiers of structural biology

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Fold assembly of small proteins using monte carlo simulations driven by restraints derived from multiple sequence alignments.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The role of a conserved proline residue in mediating conformational changes associated with voltage gating of Cx32 gap junctions

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Mutational analysis of the relative orientation of transmembrane helices I and VII in G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

9 Modeling of side chains, loops, and insertions in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Conformational constraints of amino acid side chains in alpha-helices

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Tertiary templates for proteins. Use of packing criteria in the enumeration of allowed sequences for different structural classes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Analysis of the relationship between side-chain conformation and secondary structure in globular proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Prediction of protein structure from sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Serine and threonine residues bend alpha-helices in the chi(1) = g(-) conformation.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Comparative modeling and molecular dynamics studies of the delta, kappa and mu opioid receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Theoretical study on mutation-induced activation of the luteinizing hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

A General Method for Mapping Tertiary Contacts between Amino Acid Residues in Membrane-Embedded Proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Conversion of antagonist-binding site to metal-ion site in the tachykinin NK-1 receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Partial agonism through a zinc-Ion switch constructed between transmembrane domains III and VII in the tachykinin NK(1) receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

How frequent are correlated changes in families of protein sequences?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Predicting local structural changes that result from point mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Can three-dimensional contacts in protein structures be predicted by analysis of correlated mutations?

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Conserved polar residues in the transmembrane domain of the human tachykinin NK2 receptor: functional roles and structural implications

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The ligand-binding domain of rhodopsin and other G protein-linked receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Arrangement of transmembrane domains in adrenergic receptors. Similarity to bacteriorhodopsin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Modeling of loops in protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Molecular dynamics simulations predict a tilted orientation for the helical region of dynorphin A(1-17) in dimyristoylphosphatidylcholine bilayers

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Sensitivity comparison of protein amino acid sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Protein sequence alignment techniques.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Simultaneous comparison of several sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Prediction of protein secondary structure at better than 70% accuracy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Bridging the protein sequence-structure gap by structure predictions

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Predicting protein secondary structure with a nearest-neighbor algorithm.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Patterns of divergence in homologous proteins as indicators of secondary and tertiary structure: a prediction of the structure of the catalytic domain of protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

An algorithm for secondary structure determination in proteins based on sequence similarity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Differences in conformational properties of the second intracellular loop (IL2) in 5HT(2C) receptors modified by RNA editing can account for G protein coupling efficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Conformational analysis and clustering of short and medium size loops connecting regular secondary structures: a database for modeling and prediction

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The Functional Microdomain in Transmembrane Helices 2 and 7 Regulates Expression, Activation, and Coupling Pathways of the Gonadotropin-releasing Hormone Receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Mapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Identification of conserved aromatic residues essential for agonist binding and second messenger production at 5-hydroxytryptamine2A receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Site-directed mutagenesis of the human dopamine D2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

The role of conserved aspartate and serine residues in ligand binding and in function of the 5-HT1A receptor: a site-directed mutation study

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Dopamine D4/D2 receptor selectivity is determined by A divergent aromatic microdomain contained within the second, third, and seventh membrane-spanning segments

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Specific tryptophan UV-absorbance changes are probes of the transition of rhodopsin to its active state

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Constitutive activation of the beta2 adrenergic receptor alters the orientation of its sixth membrane-spanning segment

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Ligand-induced domain motion in the activation mechanism of a G-protein-coupled receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2943145-X

7 January 2021

10.1016/S0076-6879(02)43145-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11665578%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

1 reference