TNFRSF1A associated via death domain (Q7671239)

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mammalian protein found in Homo sapiens

• tumor necrosis factor receptor-1-associated protein
• tumor necrosis factor receptor type 1-associated DEATH domain protein
• tumor necrosis factor receptor type 1 associated death domain protein
• TRADD
• TNFR1-associated death domain protein
• TNFRSF1A-associated via death domain

edit

Language	Label	Description	Also known as
English	TNFRSF1A associated via death domain	mammalian protein found in Homo sapiens	tumor necrosis factor receptor-1-associated protein tumor necrosis factor receptor type 1-associated DEATH domain protein tumor necrosis factor receptor type 1 associated death domain protein TRADD TNFR1-associated death domain protein TNFRSF1A-associated via death domain

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q15628

part of

TRADD

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q15628

Death-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q15628

TRADD, N-terminal domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q15628

TRADD, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Death domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q15628

encoded by

TRADD

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q15628

molecular function

death domain binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

kinase binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

protein binding

determination method

IPI

25 references

retrieved

8 April 2019

stated in

EVER2 protein binds TRADD to promote TNF-α-induced apoptosis

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

SH3RF2 functions as an oncogene by mediating PAK4 protein stability

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Ribosomal protein S3 interacts with TRADD to induce apoptosis through caspase dependent JNK activation

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

RAIDD is a new 'death' adaptor molecule

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Nurses replies to expectations of the nursing profession

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRs

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

The viral oncoprotein LMP1 exploits TRADD for signaling by masking its apoptotic activity

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

BS69 negatively regulates the canonical NF-kappaB activation induced by Epstein-Barr virus-derived LMP1

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Interaction of Daxx, a Fas binding protein, with sentrin and Ubc9

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

A type III effector antagonizes death receptor signalling during bacterial gut infection

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Hepatitis C virus core protein potentiates TNF-alpha-induced NF-kappaB activation through TRAF2-IKKbeta-dependent pathway

GOA

curator

AgBase

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

identical protein binding

determination method

IPI

3 references

retrieved

8 April 2019

stated in

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

8 April 2019

stated in

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

tumor necrosis factor receptor binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

protein-containing complex binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

molecular adaptor activity

determination method

IEA

IPI

2 references

retrieved

1 January 2018

stated in

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

retrieved

1 January 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

transmembrane receptor protein tyrosine kinase adaptor activity

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IPI

molecular adaptor activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

cell component

cytoplasm

determination method

IDA

IEA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

retrieved

8 April 2019

stated in

Ribosomal protein S3 interacts with TRADD to induce apoptosis through caspase dependent JNK activation

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IDA

retrieved

8 April 2019

stated in

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IDA

cytosol

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

receptor complex

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IDA

plasma membrane

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Ribosomal protein S3 interacts with TRADD to induce apoptosis through caspase dependent JNK activation

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IDA

death-inducing signaling complex

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

No death without life: vital functions of apoptotic effectors

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

membrane raft

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

cytoskeleton

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

nucleus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

protein-containing complex

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

biological process

extrinsic apoptotic signaling pathway

determination method

TAS

IMP

IEA

3 references

retrieved

8 April 2019

stated in

No death without life: vital functions of apoptotic effectors

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

retrieved

8 April 2019

stated in

Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IMP

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

positive regulation of hair follicle development

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

regulation of tumor necrosis factor-mediated signaling pathway

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

tumor necrosis factor-mediated signaling pathway

determination method

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

retrieved

8 April 2019

stated in

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

death-inducing signaling complex assembly

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

positive regulation of NF-kappaB transcription factor activity

determination method

TAS

1 reference

retrieved

21 June 2018

stated in

No death without life: vital functions of apoptotic effectors

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15628&geneProductId=UniProtKB:Q15628

determination method

TAS

positive regulation of apoptotic process

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

No death without life: vital functions of apoptotic effectors

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method

IEP

IEA

2 references

retrieved

8 April 2019

stated in

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEP

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

regulation of extrinsic apoptotic signaling pathway via death domain receptors

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

I-kappaB kinase/NF-kappaB signaling

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

activation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

extrinsic apoptotic signaling pathway via death domain receptors

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

signal transduction

determination method

TAS

IEA

2 references

retrieved

8 April 2019

stated in

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

apoptotic process

determination method

TAS

IEA

2 references

retrieved

8 April 2019

stated in

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

protein heterooligomerization

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

positive regulation of cell migration

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer

GOA

curator

ARUK-UCL

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IMP

positive regulation of inflammatory response

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer

GOA

curator

ARUK-UCL

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IMP

positive regulation of NF-kappaB transcription factor activity

determination method

IMP

TAS

2 references

retrieved

8 April 2019

stated in

No death without life: vital functions of apoptotic effectors

GOA

curator

UniProt

UniProt protein ID

Q15628

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

TAS

retrieved

8 April 2019

stated in

MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer

GOA

curator

ARUK-UCL

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IMP

cellular response to tumor necrosis factor

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer

GOA

curator

ARUK-UCL

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IMP

positive regulation of NIK/NF-kappaB signaling

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer

GOA

curator

ARUK-UCL

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IMP

transmembrane receptor protein tyrosine kinase signaling pathway

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q15628

determination method

IEA

Gene Atlas image

PBB GE TRADD 1729 at fs.png
732 × 530; 11 KB

0 references

has part(s)

TRADD, N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q15628

Death domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q15628

Identifiers

RefSeq protein ID

NP_001310481

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8717

NP_003780

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8717

XP_005256270

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8717

XP_016879304

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

8717

UniProt protein ID

Q15628

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q15628

Ensembl protein ID

ENSP00000341268

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000341268

ENSP00000462591

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000462591

PDB structure ID

1F2H

1 reference

stated in

UniProt

UniProt protein ID

Q15628

retrieved

9 August 2016

language of work or name

English

1F3V

1 reference

stated in

UniProt

UniProt protein ID

Q15628

retrieved

9 August 2016

language of work or name

English

 

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q7671239&oldid=2022910530"