Meeting report: targeting protein phosphatases-medicines for the new millenium (Q77375717)

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5 December 2019

title

Meeting report: targeting protein phosphatases-medicines for the new millenium (English)

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5 December 2019

author name string

Shenolikar S

series ordinal

1

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5 December 2019

Brautigan DL

series ordinal

2

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5 December 2019

publication date

7 November 2000

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Science's STKE : signal transduction knowledge environment

5 December 2019

published in

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5 December 2019

volume

2000

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5 December 2019

issue

57

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5 December 2019

page(s)

pe1

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

5 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 January 2018

1 reference

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Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B

21 January 2018

1 reference

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Crystal structure of human protein tyrosine phosphatase 1B

21 January 2018

1 reference

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Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

21 January 2018

1 reference

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The tumor suppressor PTEN negatively regulates insulin signaling in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Overexpression of protein-tyrosine phosphatase-1B in adipocytes inhibits insulin-stimulated phosphoinositide 3-kinase activity without altering glucose transport or Akt/Protein kinase B activation

21 January 2018

1 reference

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Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

21 January 2018

1 reference

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On target with a new mechanism for the regulation of protein phosphorylation

21 January 2018

1 reference

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A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin.

21 January 2018

1 reference

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Asp905Tyr polymorphism of the gene for the skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in NIDDM.

21 January 2018

1 reference

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Adenovirus-mediated expression of a naturally occurring Asp905Tyr variant of the glycogen-associated regulatory subunit of protein phosphatase-1 in L6 myotubes

21 January 2018

1 reference

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PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen

21 January 2018

1 reference

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Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, GL, GM/RGl) expressed in hepatocytes

21 January 2018

1 reference

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Rapid identification of protein phosphatase 1-binding proteins by mixed peptide sequencing and data base searching. Characterization of a novel holoenzymic form of protein phosphatase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Organization of kinases, phosphatases, and receptor signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Regulation of NMDA receptors by an associated phosphatase-kinase signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

A signaling complex of Ca2+-calmodulin-dependent protein kinase IV and protein phosphatase 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Regulation of protein phosphatase 2A by direct interaction with casein kinase 2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Regulation of myosin phosphatase by a specific interaction with cGMP- dependent protein kinase Ialpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSTKE.2000.57.PE1

21 January 2018

Identifiers

DOI

10.1126/STKE.2000.57.PE1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11752618%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

1 reference