Down-regulation of diabetogenic CD4+ T cells by a soluble dimeric peptide-MHC class II chimera (Q77680801)

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7 December 2019

title

Down-regulation of diabetogenic CD4+ T cells by a soluble dimeric peptide-MHC class II chimera (English)

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7 December 2019

4

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7 December 2019

5

Harald von Boehmer

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7 December 2019

author name string

Sofia Casares

1

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7 December 2019

Alicia Hurtado

2

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7 December 2019

Robert C McEvoy

3

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7 December 2019

Teodor-Doru Brumeanu

6

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7 December 2019

publication date

25 February 2002

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7 December 2019

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7 December 2019

volume

3

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7 December 2019

issue

4

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7 December 2019

page(s)

383-391

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Dissecting the genetics of type 1 diabetes: relevance for familial clustering and differences in incidence

7 December 2019

cites work

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7 January 2021

MHC class-II molecules and autoimmunity

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7 January 2021

Neonatal thymectomy prevents spontaneous diabetes mellitus in the BB/W rat.

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7 January 2021

Induction of tolerance to autoimmune diabetes with islet antigens

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NOD marrow stem cells adoptively transfer diabetes to resistant (NOD x NON)F1 mice

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7 January 2021

Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice

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Inhibition of diabetes by an insulin-reactive CD4 T-cell clone in the nonobese diabetic mouse.

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7 January 2021

Prevention of diabetes in the NOD mouse: implications for therapeutic intervention in human disease

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7 January 2021

Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice

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7 January 2021

Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice

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7 January 2021

Early prophylaxis with recombinant human interleukin-11 prevents spontaneous diabetes in NOD mice

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7 January 2021

Interleukin-13 prevents autoimmune diabetes in NOD mice

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7 January 2021

Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process

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7 January 2021

Prevention of autoimmune diabetes with nonactivating anti-CD3 monoclonal antibody

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7 January 2021

Autoimmune diabetes in NOD mouse is L3T4 T-lymphocyte dependent

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7 January 2021

Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes

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7 January 2021

Prevention of autoimmune but not allogeneic destruction of grafted islets by different therapeutic strategies

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7 January 2021

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

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7 January 2021

Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)

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7 January 2021

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

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7 January 2021

Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice

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7 January 2021

Regulatory Th2-type T cell lines against insulin and GAD peptides derived from orally- and nasally-treated NOD mice suppress diabetes

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7 January 2021

Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein.

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7 January 2021

Treatment of NOD diabetes with a novel peptide of the hsp60 molecule induces Th2-type antibodies

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7 January 2021

Treatment with GAD65 or BSA does not protect against diabetes in BB rats

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7 January 2021

Effect of intrathymic administration of mycobacterial heat shock protein 65 and peptide p277 on the development of diabetes in NOD mice: caution required in vaccination studies.

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7 January 2021

Foreign peptides expressed in engineered chimeric self molecules

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7 January 2021

Engineering and characterization of a murine MHC class II-immunoglobulin chimera expressing an immunodominant CD4 T viral epitope

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7 January 2021

T-cell tolerance and autoimmune diabetes

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7 January 2021

Enzymatically mediated engineering of multivalent MHC class II-peptide chimeras

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7 January 2021

Antigen-specific signaling by a soluble, dimeric peptide/major histocompatibility complex class II/Fc chimera leading to T helper cell type 2 differentiation

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7 January 2021

Potent T cell activation with dimeric peptide-major histocompatibility complex class II ligand: the role of CD4 coreceptor

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7 January 2021

Kinetics of T-cell receptor binding by bivalent HLA-DR. Peptide complexes that activate antigen-specific human T-cells

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7 January 2021

Anergy induction by dimeric TCR ligands

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7 January 2021

Escape from self-tolerance leads to neonatal insulin-dependent diabetes mellitus

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7 January 2021

Changes in function of antigen-specific lymphocytes correlating with progression towards diabetes in a transgenic model.

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7 January 2021

A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity

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7 January 2021

Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells

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7 January 2021

Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptors

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7 January 2021

T-regulatory 1 cells: a novel subset of CD4 T cells with immunoregulatory properties.

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7 January 2021

An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus

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7 January 2021

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7 January 2021

The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands

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7 January 2021

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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7 January 2021

Proliferative responses of blood mononuclear cells (BMNC) in a cohort of elderly humans: role of lymphocyte phenotype and cytokine production

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7 January 2021

Characterization of peripheral regulatory CD4+ T cells that prevent diabetes onset in nonobese diabetic mice

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7 January 2021

CD4+CD8- thymocytes that express L-selectin protect rats from diabetes upon adoptive transfer

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7 January 2021

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

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7 January 2021

Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.

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7 January 2021

Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients

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7 January 2021

Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.

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7 January 2021

Identifiers

DOI

10.1038/NI770

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7 December 2019

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