tyrosine kinase 2 (Q7861688)

SH2 domain superfamily

1 reference

tyrosine-protein kinase, non-receptor Jak/Tyk2

1 reference

FERM superfamily, second domain

1 reference

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

SH2 domain, protein family

1 reference

Band 4.1 domain, protein family

1 reference

Tyrosine-protein kinase, non-receptor, TYK2, N-terminal domain, protein family

1 reference

FERM domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

protein kinase activity

1 reference

8 April 2019

type 1 angiotensin receptor binding

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

growth hormone receptor binding

1 reference

8 April 2019

The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

5 references

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

Structural basis of recognition of interferon-α receptor by tyrosine kinase 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

protein tyrosine kinase activity

IPI

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

2 references

non-membrane spanning protein tyrosine kinase activity

5 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

17 October 2017

tyk2, prototype of a novel class of non-receptor tyrosine kinase genes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

non-membrane spanning protein tyrosine kinase activity

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

tyk2, prototype of a novel class of non-receptor tyrosine kinase genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

1 reference

8 April 2019

The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

extrinsic component of cytoplasmic side of plasma membrane

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

extracellular exosome

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

1 reference

8 April 2019

The growth hormone receptor associates with Jak1, Jak2 and Tyk2 in human liver

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

IDA

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

intracellular signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

regulation of type I interferon-mediated signaling pathway

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

regulation of cell population proliferation

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

type I interferon signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

peptidyl-tyrosine autophosphorylation

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

innate immune response

1 reference

17 October 2017

1 reference

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P29597&geneProductId=UniProtKB:P29597

interleukin-12-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

peptidyl-tyrosine phosphorylation

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

cytokine-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

interleukin-23-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

interleukin-27-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P29597

physically interacts with

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

5688

tyrosine-protein kinase, active site

English

retrieved

17 August 2016

Gene Atlas image

PBB GE TYK2 205546 s at fs.png
732 × 530; 11 KB

0 references

has part(s)

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

SH2 domain

1 reference

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

Band 4.1 domain

1 reference

Tyrosine-protein kinase, non-receptor, TYK2, N-terminal

1 reference

FERM domain

1 reference

D08.811.913.696.620.682.725.124.650

Identifiers

MeSH descriptor ID

D053634

subject named as

TYK2 Kinase

0 references

MeSH tree code

0 references

D12.776.476.568.124.650

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference