Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress (Q78624852)

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15 December 2019

title

Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress (English)

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15 December 2019

5

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15 December 2019

author name string

Eveline Hütter

1

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15 December 2019

Hermann Unterluggauer

2

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15 December 2019

Florian Uberall

3

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15 December 2019

Herbert Schramek

4

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15 December 2019

publication date

1 October 2002

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15 December 2019

published in

Experimental Gerontology

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15 December 2019

volume

37

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15 December 2019

issue

10-11

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15 December 2019

page(s)

1165-1174

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The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs).

15 December 2019

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Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication

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Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts

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Implication of atypical protein kinase C isozymes lambda and zeta in Ras mediated reorganization of the actin cytoskeleton and cyclin D1-induction

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Transcriptional activation of c-fos by oncogenic Ha-Ras in mouse mammary epithelial cells requires the combined activities of PKC-lambda, epsilon and zeta

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Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras

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Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

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Role for mitochondrial oxidants as regulators of cellular metabolism

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Ras protein signalling

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Integrating stress-response and cell-cycle checkpoint pathways

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Increase of oxidatively modified protein is associated with a decrease of proteasome activity and content in aging epidermal cells

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7 January 2021

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7 January 2021

Lack of Elk-1 phosphorylation and dysregulation of the extracellular regulated kinase signaling pathway in senescent human fibroblast.

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Detection of ERK activation by a novel monoclonal antibody

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7 January 2021

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

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Identifiers

DOI

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15 December 2019

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