Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses (Q79370627)

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22 December 2019

title

Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses (English)

1 reference

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22 December 2019

author name string

Jr-Wen Shui

1

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22 December 2019

Jonathan S Boomer

2

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22 December 2019

Jin Han

3

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22 December 2019

Jun Xu

4

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22 December 2019

Gregory A Dement

5

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22 December 2019

Guisheng Zhou

6

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22 December 2019

Tse-Hua Tan

7

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22 December 2019

publication date

19 November 2006

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22 December 2019

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22 December 2019

volume

8

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22 December 2019

page(s)

84-91

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22 December 2019

issue

1

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Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade

22 December 2019

cites work

1 reference

7 January 2021

Functional interactions of HPK1 with adaptor proteins

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7 January 2021

HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway

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7 January 2021

Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1)

1 reference

7 January 2021

Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB

1 reference

7 January 2021

HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.

1 reference

7 January 2021

Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling

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7 January 2021

The adaptor protein Gads (Grb2-related adaptor downstream of Shc) is implicated in coupling hemopoietic progenitor kinase-1 to the activated TCR.

1 reference

7 January 2021

Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes

1 reference

7 January 2021

Synergistic regulation of immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1.

1 reference

7 January 2021

HIP-55 is important for T-cell proliferation, cytokine production, and immune responses

1 reference

7 January 2021

A novel src homology 3 domain-containing adaptor protein, HIP-55, that interacts with hematopoietic progenitor kinase 1

1 reference

7 January 2021

The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling

1 reference

7 January 2021

Hematopoietic progenitor kinase 1 (HPK1) negatively regulates prostaglandin E2-induced fos gene transcription

1 reference

7 January 2021

Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates IkappaB kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase

1 reference

7 January 2021

Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase

1 reference

7 January 2021

Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes

1 reference

7 January 2021

Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and function

1 reference

7 January 2021

Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells

1 reference

7 January 2021

Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine

1 reference

7 January 2021

The structural basis for 14-3-3:phosphopeptide binding specificity

1 reference

7 January 2021

c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation

1 reference

7 January 2021

ICOS co-stimulatory receptor is essential for T-cell activation and function

1 reference

7 January 2021

Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription

1 reference

7 January 2021

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

1 reference

7 January 2021

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

7 January 2021

Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.

1 reference

7 January 2021

Vav1 Transduces T Cell Receptor Signals to the Activation of the Ras/ERK Pathway via LAT, Sos, and RasGRP1

1 reference

7 January 2021

The linker phosphorylation site Tyr292 mediates the negative regulatory effect of Cbl on ZAP-70 in T cells

1 reference

7 January 2021

Cbl functions downstream of Src kinases in Fc gamma RI signaling in primary human macrophages

1 reference

7 January 2021

Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis

1 reference

7 January 2021

A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway

1 reference

7 January 2021

Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase

1 reference

7 January 2021

A novel human SPS1/STE20 homologue, KHS, activates Jun N-terminal kinase

1 reference

7 January 2021

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

1 reference

7 January 2021

Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1.

1 reference

7 January 2021

JNK2 is a positive regulator of the cJun transcription factor

1 reference

7 January 2021

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry

1 reference

7 January 2021

Activation-modulated association of 14-3-3 proteins with Cbl in T cells

1 reference

7 January 2021

Regulatory role of p53 in experimental autoimmune encephalomyelitis

1 reference

7 January 2021

Protein phosphatase 4 is involved in tumor necrosis factor-alpha-induced activation of c-Jun N-terminal kinase

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI1416

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17115060%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

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