Investigation of interleukin 1beta-mediated regulation of NF-kappaB activation in colonic cells reveals divergence between PKB and PDK-transduced events (Q79394740)

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scientific article published on 30 November 2006

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English	Investigation of interleukin 1beta-mediated regulation of NF-kappaB activation in colonic cells reveals divergence between PKB and PDK-transduced events	scientific article published on 30 November 2006

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scholarly article

1 reference

Europe PubMed Central

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22 December 2019

Investigation of interleukin 1beta-mediated regulation of NF-kappaB activation in colonic cells reveals divergence between PKB and PDK-transduced events (English)

1 reference

Europe PubMed Central

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22 December 2019

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Ken Kuljit Singh Parhar

1

1 reference

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22 December 2019

Antonio Gomez-Muñoz

4

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22 December 2019

author name string

Sharlene Eivemark

2

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22 December 2019

Kiran Assi

3

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22 December 2019

Arthur Yee

5

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22 December 2019

Baljinder Salh

6

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22 December 2019

publication date

30 November 2006

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22 December 2019

Molecular and Cellular Biochemistry

1 reference

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22 December 2019

300

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22 December 2019

1-2

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22 December 2019

113-127

1 reference

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22 December 2019

https://scigraph.springernature.com/pub.10.1007/s11010-006-9375-4

0 references

3'-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The serine protease inhibitors, tosylphenylalanine chloromethyl ketone and tosyllysine chloromethyl ketone, potently inhibit pp70s6k activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of nuclear transcription factor NF-kappaB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of the p65 subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IKK beta and phosphatidylinositol 3-kinase/Akt participate in non-pathogenic Gram-negative enteric bacteria-induced RelA phosphorylation and NF-kappa B activation in both primary and intestinal epithelial cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on mechanism of action of anti-tumor-promoting agents: their specificity in two-stage promotion

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The essential role of MEKK3 in TNF-induced NF-kappaB activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles for homotypic interactions and transautophosphorylation in IkappaB kinase beta IKKbeta) activation [corrected].

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

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Phosphorylation of NF-kappa B by calmodulin-dependent kinase IV activates anti-apoptotic gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The I kappa B/NF-kappa B system: a key determinant of mucosalinflammation and protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

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Direct evidence for the presence of histidine in the active center of chymotrypsin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Hsp90 in signaling and stability of 3-phosphoinositide-dependent kinase-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulated production of interferon-inducible T-cell chemoattractants by human intestinal epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of NF-kappaB/Rel induces apoptosis of murine B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

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Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB regulation in the immune system

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

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Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential and regulated expression of C-X-C, C-C, and C-chemokines by human colon epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumorigenesis in Mouse Skin: Inhibition by Synthetic Inhibitors of Proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of serine 276 is essential for p65 NF-kappaB subunit-dependent cellular responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinase regulation in inflammatory response

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of 3-phosphoinositide-dependent kinase 1 (PDK1) signaling by the anti-tumorigenic and anti-proliferative agent n-alpha-tosyl-l-phenylalanyl chloromethyl ketone

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unravelling the activation mechanisms of protein kinase B/Akt

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PCR-mediated recombination and mutagenesis. SOEing together tailor-made genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors: critical proteins linking innate and acquired immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to bacterial lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/17136479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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