Molecular modeling of the von Willebrand factor A2 Domain and the effects of associated type 2A von Willebrand disease mutations (Q80477437)

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31 December 2019

title

Molecular modeling of the von Willebrand factor A2 Domain and the effects of associated type 2A von Willebrand disease mutations (English)

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4

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31 December 2019

author name string

Jeffrey J Sutherland

series ordinal

1

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31 December 2019

Lee A O'Brien

series ordinal

2

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31 December 2019

David Lillicrap

series ordinal

3

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31 December 2019

publication date

3 August 2004

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Journal of Molecular Modeling

31 December 2019

published in

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31 December 2019

volume

10

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31 December 2019

page(s)

259-270

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31 December 2019

issue

4

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https://scigraph.springernature.com/pub.10.1007/s00894-004-0194-9

31 December 2019

exact match

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cites work

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Assessment of protein fold predictions from sequence information: the predicted alpha/beta doubly wound fold of the von Willebrand factor type A domain is similar to its crystal structure

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Hybrid fold recognition: combining sequence derived properties with evolutionary information.

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Binding of von Willebrand factor to glycoproteins Ib and IIb/IIIa complex: affinity is related to multimeric size

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Recombinant vWF type 2A mutants R834Q and R834W show a defect in mediating platelet adhesion to collagen, independent of enhanced sensitivity to a plasma protease

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Molecular modeling of ligand and mutation sites of the type A domains of human von Willebrand factor and their relevance to von Willebrand's disease.

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Assembly and routing of von Willebrand factor variants: the requirements for disulfide-linked dimerization reside within the carboxy-terminal 151 amino acids

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Genetic linkage of two intragenic restriction fragment length polymorphisms with von Willebrand's disease type IIA. Evidence for a defect in the von Willebrand factor gene

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Characterization of Leu777Pro and Ile865Thr type IIA von Willebrand disease mutations

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12 December 2020

All-atom empirical potential for molecular modeling and dynamics studies of proteins

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Comparison of sequence profiles. Strategies for structural predictions using sequence information

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Impaired intracellular transport produced by a subset of type IIA von Willebrand disease mutations

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A general method applicable to the search for similarities in the amino acid sequence of two proteins

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The protein fold of the von Willebrand factor type A domain is predicted to be similar to the open twisted beta-sheet flanked by alpha-helices found in human ras-p21.

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12 December 2020

Recognition of errors in three-dimensional structures of proteins

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12 December 2020

Identification of disulfide-bridged substructures within human von Willebrand factor

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12 December 2020

The structure and function of von Willebrand factor

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12 December 2020

The interpretation of protein structures: Estimation of static accessibility

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12 December 2020

The Pfam protein families database

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12 December 2020

Generation and characterization of peptide-specific antibodies that inhibit von Willebrand factor binding to glycoprotein IIb-IIIa without interacting with other adhesive molecules. Selectivity is conferred by Pro1743 and other amino acid residues a

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12 December 2020

Identification of a cleavage site directing the immunochemical detection of molecular abnormalities in type IIA von Willebrand factor

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12 December 2020

VWF73, a region from D1596 to R1668 of von Willebrand factor, provides a minimal substrate for ADAMTS-13

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12 December 2020

Identification of common molecular subsequences

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12 December 2020

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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12 December 2020

10.1007/S00894-004-0194-9

Identifiers

DOI

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31 December 2019

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