Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping (Q81099032)

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scientific article published on 06 September 2007

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English	Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping	scientific article published on 06 September 2007

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scholarly article

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5 January 2020

Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping (English)

1 reference

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5 January 2020

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author name string

Haferlach C

1

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5 January 2020

Dicker F

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5 January 2020

Schnittger S

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Kern W

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5 January 2020

Haferlach T

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publication date

6 September 2007

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2442-2451

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5 January 2020

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404935

0 references

Prognosis at diagnosis: integrating molecular biologic insights into clinical practice for patients with CLL

1 reference

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The role of prognostic factors in assessing 'high-risk' subgroups of patients with chronic lymphocytic leukemia

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7 January 2021

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Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities

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Genomic aberrations and survival in chronic lymphocytic leukemia

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Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.

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CD40L stimulation enhances the ability of conventional metaphase cytogenetics to detect chromosome aberrations in B-cell chronic lymphocytic leukaemia cells

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7 January 2021

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Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27

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Immunostimulatory oligonucleotide-induced metaphase cytogenetics detect chromosomal aberrations in 80% of CLL patients: A study of 132 CLL cases with correlation to FISH, IgVH status, and CD38 expression

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Improvement of the chronic lymphocytic leukemia scoring system with the monoclonal antibody SN8 (CD79b).

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Loss of genetic material is more common than gain in acute myeloid leukemia with complex aberrant karyotype: a detailed analysis of 125 cases using conventional chromosome analysis and fluorescence in situ hybridization including 24-color FISH.

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7 January 2021

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Comparison of chromosome banding analysis, interphase- and hypermetaphase-FISH, qualitative and quantitative PCR for diagnosis and for follow-up in chronic myeloid leukemia: a study on 350 cases.

1 reference

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7 January 2021

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CyDAS: a cytogenetic data analysis system

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7 January 2021

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Proposals for standardized protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes

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ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia.

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7 January 2021

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ZAP-70 expression and prognosis in chronic lymphocytic leukaemia

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7 January 2021

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ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

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Chronic lymphocytic leukaemia profiled for prognosis using a fluorescence in situ hybridisation panel

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7 January 2021

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Molecular cytogenetic analysis of B-cell chronic lymphocytic leukemia

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7 January 2021

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Chromosomal translocations are associated with poor prognosis in chronic lymphocytic leukemia.

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Chromosomal translocations independently predict treatment failure, treatment-free survival and overall survival in B-cell chronic lymphocytic leukemia patients treated with cladribine

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Genetics of chronic lymphocytic leukemia: genomic aberrations and V(H) gene mutation status in pathogenesis and clinical course

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Chromosome anomalies detected by interphase fluorescence in situ hybridization: correlation with significant biological features of B-cell chronic lymphocytic leukaemia

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Comparative analysis of flow cytometric techniques in assessment of ZAP-70 expression in relation to IgVH mutational status in chronic lymphocytic leukemia

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An optimized whole blood method for flow cytometric measurement of ZAP-70 protein expression in chronic lymphocytic leukemia

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Immunologic and cytogenetic studies improve prognosis prediction in chronic B-lymphocytic leukemia. A multivariate analysis of 24 variables.

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7 January 2021

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Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile

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Genome-wide analysis of DNA copy number changes and LOH in CLL using high-density SNP arrays.

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Genes and chromosomes in chronic B-cell leukemia

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Microarray gene expression profiling of B-cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status

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Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy

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