The secreted form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumour effects (Q82305649)

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15 January 2020

title

The secreted form of the p40 subunit of interleukin (IL)-12 inhibits IL-23 functions and abrogates IL-23-mediated antitumour effects (English)

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15 January 2020

4

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15 January 2020

author name string

Osamu Shimozato

1

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15 January 2020

Shin-ichi Ugai

2

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15 January 2020

Masako Chiyo

3

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15 January 2020

Hiroyasu Nagakawa

5

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15 January 2020

Akihiko Wada

6

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15 January 2020

Kiyoko Kawamura

7

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15 January 2020

Hiroshi Yamamoto

8

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15 January 2020

Masatoshi Tagawa

9

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publication date

1 January 2006

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15 January 2020

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15 January 2020

volume

117

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15 January 2020

issue

1

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15 January 2020

page(s)

22-28

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A protective and agonistic function of IL-12p40 in mycobacterial infection.

15 January 2020

cites work

1 reference

12 December 2020

Characterization of IL-12 receptor beta1 chain (IL-12Rbeta1)-deficient mice: IL-12Rbeta1 is an essential component of the functional mouse IL-12 receptor

1 reference

12 December 2020

A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

1 reference

12 December 2020

IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination

1 reference

12 December 2020

Impaired accumulation and function of memory CD4 T cells in human IL-12 receptor beta 1 deficiency

1 reference

12 December 2020

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

1 reference

12 December 2020

Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system

1 reference

12 December 2020

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

12 December 2020

IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity

1 reference

12 December 2020

Antitumor and antimetastatic activity of IL-23

1 reference

12 December 2020

Induction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophages

1 reference

12 December 2020

Role of IL-12 Receptor β1 in Regulation of T Cell Response by APC in Experimental Autoimmune Encephalomyelitis

1 reference

12 December 2020

IL-12 receptor deficiency revisited: IL-23-mediated signaling is also impaired in human genetic IL-12 receptor beta1 deficiency

1 reference

12 December 2020

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

1 reference

12 December 2020

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

1 reference

12 December 2020

The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer

1 reference

12 December 2020

Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity

1 reference

12 December 2020

Assessment of animal models for MS and demyelinating disease in the design of rational therapy

1 reference

12 December 2020

Protective immunity is induced in murine colon carcinoma cells by the expression of interleukin-12 or interleukin-18, which activate type 1 helper T cells

1 reference

12 December 2020

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

1 reference

12 December 2020

Antigen-specific T cell-mediated gene therapy in collagen-induced arthritis

1 reference

12 December 2020

Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

1 reference

12 December 2020

Adoptive immunotherapy of experimental autoimmune encephalomyelitis via T cell delivery of the IL-12 p40 subunit

1 reference

12 December 2020

IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis.

1 reference

12 December 2020

Induction of systemic immunity by expression of interleukin-23 in murine colon carcinoma cells

1 reference

12 December 2020

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

1 reference

12 December 2020

Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist

1 reference

12 December 2020

Local production of the p40 subunit of interleukin 12 suppresses T-helper 1-mediated immune responses and prevents allogeneic myoblast rejection

1 reference

12 December 2020

Differential effects of IL-12 receptor blockade with IL-12 p40 homodimer on the induction of CD4+ and CD8+ IFN-gamma-producing cells

1 reference

12 December 2020

Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells

1 reference

12 December 2020

Selective expression of an interleukin-12 receptor component by human T helper 1 cells

1 reference

12 December 2020

IL-23 and IL-12 have overlapping, but distinct, effects on murine dendritic cells

1 reference

12 December 2020