QT prolongation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite paliperidone (Q82818835)

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17 January 2020

title

QT prolongation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite paliperidone (English)

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17 January 2020

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Yutaro Suzuki

1

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17 January 2020

Naoki Fukui

2

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17 January 2020

Junzo Watanabe

3

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17 January 2020

Shin Ono

4

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17 January 2020

Takuro Sugai

5

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Nobuto Tsuneyama

6

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Mami Saito

7

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Yoshimasa Inoue

8

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Toshiyuki Someya

9

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publication date

5 December 2011

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17 January 2020

published in

Human Psychopharmacology

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volume

27

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issue

1

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page(s)

39-42

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Paliperidone extended release: a review of its use in the management of schizophrenia

17 January 2020

cites work

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7 January 2021

A randomized double-blind study of risperidone and olanzapine in the treatment of schizophrenia or schizoaffective disorder

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7 January 2021

Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4

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7 January 2021

Risperidone prolongs cardiac action potential through reduction of K+ currents in rabbit myocytes

1 reference

7 January 2021

QT interval: how to measure it and what is "normal"

1 reference

7 January 2021

A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition

1 reference

7 January 2021

Cardiac arrest and ventricular arrhythmia in patients taking antipsychotic drugs: cohort study using administrative data

1 reference

7 January 2021

The role of CYP2D6 and ABCB1 pharmacogenetics in drug-naïve patients with first-episode schizophrenia treated with risperidone

1 reference

7 January 2021

Predominant role of the 9-hydroxy metabolite of risperidone in elevating blood prolactin levels

1 reference

7 January 2021

Prolactin elevation of the antipsychotic risperidone is predominantly related to its 9-hydroxy metabolite

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7 January 2021

Effect of verapamil on pharmacokinetics and pharmacodynamics of risperidone: in vivo evidence of involvement of P-glycoprotein in risperidone disposition

1 reference

7 January 2021

Atypical antipsychotic drugs and the risk of sudden cardiac death

1 reference

7 January 2021

Gender differences in the relationship between the risperidone metabolism and the plasma prolactin levels in psychiatric patients

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7 January 2021

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

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7 January 2021

Sex differences in repolarization homogeneity and its circadian pattern

1 reference

7 January 2021

Circadian and sex-dependent QT dynamics

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7 January 2021

Double-blind comparison of olanzapine versus risperidone in the treatment of schizophrenia and other psychotic disorders.

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7 January 2021

Prolongation of cardiac ventricular repolarization under paliperidone: how and how much?

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7 January 2021

Identifiers

DOI

10.1002/HUP.1258

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17 January 2020

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