Epigenetic silencing of PTPRR activates MAPK signaling, promotes metastasis and serves as a biomarker of invasive cervical cancer (Q83435245)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22330137%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Epigenetic silencing of PTPRR activates MAPK signaling, promotes metastasis and serves as a biomarker of invasive cervical cancer (English)

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22 January 2020

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cervix uterine cancer

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9

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22 January 2020

author name string

P-H Su

1

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22 January 2020

Y-W Lin

2

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22 January 2020

R-L Huang

3

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22 January 2020

Y-P Liao

4

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22 January 2020

H-Y Lee

5

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22 January 2020

H-C Wang

6

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22 January 2020

T-K Chao

7

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22 January 2020

C-K Chen

8

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22 January 2020

T-Y Chu

10

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22 January 2020

M-H Yu

11

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22 January 2020

H-C Lai

12

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22 January 2020

publication date

13 February 2012

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22 January 2020

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22 January 2020

volume

32

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22 January 2020

issue

1

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22 January 2020

page(s)

15-26

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https://scigraph.springernature.com/pub.10.1038/onc.2012.29

22 January 2020

exact match

0 references

cites work

Cervical carcinoma and human papillomavirus: on the road to preventing a major human cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Human papillomavirus oncoproteins: pathways to transformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Genetic determinants of cancer metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

31 March 2020

Epigenetics in cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Epigenetic contributions to cancer metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

31 March 2020

Epigenetics in cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Epigenetic reprogramming of host genes in viral and microbial pathogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

The natural history of cervical HPV infection: unresolved issues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Promoter methylation of SFRPs gene family in cervical cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Characterization of LMX-1A as a metastasis suppressor in cervical cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Methylation analysis of SFRP genes family in cervical adenocarcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Utility of methylation markers in cervical cancer early detection: appraisal of the state-of-the-science

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Identification of novel DNA methylation markers in cervical cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

SFRP1 and SFRP2 suppress the transformation and invasion abilities of cervical cancer cells through Wnt signal pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Increased gene copy numbers at chromosome 20q are frequent in both squamous cell carcinomas and adenocarcinomas of the cervix

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

HPV16 E6 augments Wnt signaling in an E6AP-dependent manner

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Silencing oncogene expression in cervical cancer stem-like cells inhibits their cell growth and self-renewal ability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Tyrosine-specific MAPK phosphatases and the control of ERK signaling in PC12 cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

PTPRR, cerebellum, and motor coordination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Role of Ras signaling in the induction of snail by transforming growth factor-beta.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-kappaB/Snail1 pathway.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

DNA methylation in ovarian cancer. II. Expression of DNA methyltransferases in ovarian cancer cell lines and normal ovarian epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Breast cancer epigenetics: from DNA methylation to microRNAs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

DNA methyltransferase DNMT3b protein overexpression as a prognostic factor in patients with diffuse large B-cell lymphomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Down-regulation of DNMT3b in PC3 cells effects locus-specific DNA methylation, and represses cellular growth and migration

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

CpG methylation is maintained in human cancer cells lacking DNMT1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Rethinking how DNA methylation patterns are maintained

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Protein-tyrosine phosphatases and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Altered MAP kinase phosphorylation and impaired motor coordination in PTPRR deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Metastasis suppressor genes: from gene identification to protein function and regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Phosphotyrosine-specific phosphatase PTP-SL regulates the ERK5 signaling pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Induction of the HPV16 enhancer activity by Jun-B and c-Fos through cooperation of the promoter-proximal AP-1 site and the epithelial cell type--specific regulatory element in fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

AP-1: a double-edged sword in tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Constitutively active MEK1 is sufficient to induce epithelial-to-mesenchymal transition in intestinal epithelial cells and to promote tumor invasion and metastasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Expression of AP1 during cellular differentiation determines human papillomavirus E6/E7 expression in stratified epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

IL-13 regulates cancer invasion and metastasis through IL-13Rα2 via ERK/AP-1 pathway in mouse model of human ovarian cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Activator protein 1 (AP-1) contributes to EpCAM-dependent breast cancer invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Silencing of E7 oncogene restores functional E-cadherin expression in human papillomavirus 16-transformed keratinocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Viral oncoproteins target the DNA methyltransferases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Epigenetic repression of E-cadherin by human papillomavirus 16 E7 protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

The molecular biology of head and neck cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Epithelial-mesenchymal transitions in development and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

HPV16 E7 oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesenchymal transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Antibody diversity: one enzyme to rule them all.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Abnormal distribution of E-cadherin and beta-catenin in different histologic types of cancer of the uterine cervix

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

What will it take to obtain DNA methylation markers for early cervical cancer detection?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Epigenetic alterations in cervical carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29

Identification of novel methylation markers in cervical cancer using restriction landmark genomic scanning

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.29