The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice (Q83924412)

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29 January 2020

title

The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice (English)

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29 January 2020

13

Shuh Narumiya

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29 January 2020

author name string

Naoki Nakagawa

1

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29 January 2020

Koh-ichi Yuhki

2

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29 January 2020

Jun-ichi Kawabe

3

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29 January 2020

Takayuki Fujino

4

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29 January 2020

Osamu Takahata

5

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29 January 2020

Maki Kabara

6

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29 January 2020

Kazutoshi Abe

7

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29 January 2020

Fumiaki Kojima

8

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29 January 2020

Hitoshi Kashiwagi

9

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29 January 2020

Naoyuki Hasebe

10

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29 January 2020

Kenjiro Kikuchi

11

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29 January 2020

Yukihiko Sugimoto

12

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29 January 2020

Fumitaka Ushikubi

14

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language of work or name

English

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publication date

18 April 2012

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29 January 2020

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29 January 2020

volume

82

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29 January 2020

page(s)

158-171

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29 January 2020

issue

2

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https://scigraph.springernature.com/pub.10.1038/ki.2012.115

29 January 2020

exact match

0 references

cites work

Mechanisms of tubulointerstitial fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury?

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

https://api.crossref.org/works/10.1038%2FKI.2012.115

1 reference

7 January 2021

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Chemokines and chemokine receptors are involved in the resolution or progression of renal disease.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Obstructive nephropathy: insights from genetically engineered animals

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Epithelial-mesenchymal transition and its implications for fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

The basics of epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Evidence that fibroblasts derive from epithelium during tissue fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Metabolic and cellular alterations underlying the exaggerated renal prostaglandin and thromboxane synthesis in ureter obstruction in rabbits. Inflammatory response involving fibroblasts and mononuclear cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Prostanoid receptors: structures, properties, and functions

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

EP2 and EP4 prostanoid receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Cytokines in epithelial-mesenchymal transition: a new insight into obstructive nephropathy

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Inflammatory mediators and growth factors in obstructive renal injury

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Increased cyclooxygenase-2 expression and prostaglandin E2 production in pressurized renal medullary interstitial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Urinary tract obstruction induces transient accumulation of COX-2-derived prostanoids in kidney tissue

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Immunological aspects of acute ureteral obstruction: immune cell infiltrate in the kidney

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Angiotensin II type 2 receptor deficiency aggravates renal injury and reduces survival in chronic kidney disease in mice.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Scar wars: mapping the fate of epithelial-mesenchymal-myofibroblast transition

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Prostaglandin E2 is a potent inhibitor of epithelial-to-mesenchymal transition: interaction with hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Prostaglandin E2 suppresses chemokine production in human macrophages through the EP4 receptor

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

A novel prostaglandin E receptor 4-associated protein participates in antiinflammatory signaling

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Regulation of TNFalpha and interleukin-10 production by prostaglandins I(2) and E(2): studies with prostaglandin receptor-deficient mice and prostaglandin E-receptor subtype-selective synthetic agonists

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Prostaglandin E2 synthesis and suppression of fibroblast proliferation by alveolar epithelial cells is cyclooxygenase-2-dependent.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Prostaglandin E2, an immunoactivator.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Cycloxygenase-2 is expressed in vasculature of normal and ischemic adult human kidney and is colocalized with vascular prostaglandin E2 EP4 receptors

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Angiotensin II is mitogenic for human lung fibroblasts via activation of the type 1 receptor.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

In vivo bradykinin B2 receptor activation reduces renal fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Patent ductus arteriosus and neonatal death in prostaglandin receptor EP4-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Decreased susceptibility to renovascular hypertension in mice lacking the prostaglandin I2 receptor IP

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP4.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Design and synthesis of a selective EP4-receptor agonist. Part 4: practical synthesis and biological evaluation of a novel highly selective EP4-receptor agonist

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Revascularization of swine renal artery stenosis improves renal function but not the changes in vascular structure

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

The role of prostaglandin E receptor subtypes (EP1, EP2, EP3, and EP4) in bone resorption: an analysis using specific agonists for the respective EPs

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021

Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction

1 reference

https://api.crossref.org/works/10.1038%2FKI.2012.115

7 January 2021