Glutamic acid decarboxylase epitope protects against autoimmune diabetes through activation of Th2 immune response and induction of possible regulatory mechanism (Q84081029)

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scientific article published on 18 April 2010

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English	Glutamic acid decarboxylase epitope protects against autoimmune diabetes through activation of Th2 immune response and induction of possible regulatory mechanism	scientific article published on 18 April 2010

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31 January 2020

Glutamic acid decarboxylase epitope protects against autoimmune diabetes through activation of Th2 immune response and induction of possible regulatory mechanism (English)

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31 January 2020

author name string

Zhaohui Gong

1

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31 January 2020

Lin Pan

2

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31 January 2020

Yanping Le

3

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Qiong Liu

4

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31 January 2020

Mi Zhou

5

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Wenhua Xing

6

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Renjie Zhuo

7

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31 January 2020

Shaomin Wang

8

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31 January 2020

Junming Guo

9

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publication date

18 April 2010

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28

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24

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4052-4058

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31 January 2020

1 reference

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7 January 2021

Oral administration of the immunodominant B-chain of insulin reduces diabetes in a co-transfer model of diabetes in the NOD mouse and is associated with a switch from Th1 to Th2 cytokines

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7 January 2021

Human insulin B chain but not A chain decreases the rate of diabetes in BB rats.

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7 January 2021

Antigen based therapies to prevent diabetes in NOD mice

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7 January 2021

Insulin in diabetes prevention

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7 January 2021

A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes

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7 January 2021

Expression of cholera toxin B subunit oligomers in transgenic potato plants.

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7 January 2021

Oral administration of cholera toxin B-insulin conjugates protects NOD mice from autoimmune diabetes by inducing CD4+ regulatory T-cells

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7 January 2021

A plant-based cholera toxin B subunit-insulin fusion protein protects against the development of autoimmune diabetes

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7 January 2021

Oral administration of a cholera toxin B subunit-insulin fusion protein produced in silkworm protects against autoimmune diabetes

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7 January 2021

The pathogenesis of insulin-dependent diabetes mellitus

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7 January 2021

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

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7 January 2021

Importance of GAD65 peptides and I-Ag7 in the development of insulitis in nonobese diabetic mice

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7 January 2021

Regulatory and effector CD4 T cells in nonobese diabetic mice recognize overlapping determinants on glutamic acid decarboxylase and use distinct V beta genes

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7 January 2021

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

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7 January 2021

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

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7 January 2021

Cloning, expression, purification and characterization of the cholera toxin B subunit and triple glutamic acid decarboxylase epitopes fusion protein in Escherichia coli

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7 January 2021

Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance

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7 January 2021

Suppression of diabetes in non-obese diabetic (NOD) mice by oral administration of a cholera toxin B subunit-insulin B chain fusion protein vaccine produced in silkworm

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7 January 2021

Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin

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7 January 2021

Transgenic plants expressing autoantigens fed to mice to induce oral immune tolerance

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7 January 2021

Oral tolerance: therapeutic implications for autoimmune diseases

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7 January 2021

Induction of a type 1 regulatory CD4 T cell response following V beta 8.2 DNA vaccination results in immune deviation and protection from experimental autoimmune encephalomyelitis

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7 January 2021

A Th1-recognized peptide P277, when tandemly repeated, enhances a Th2 immune response toward effective vaccines against autoimmune diabetes in nonobese diabetic mice

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Responses of NOD congenic mice to a glutamic acid decarboxylase-derived peptide

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Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice

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Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase.

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Molecular profile of the T cell receptors of regulatory and effector CD4+ T cells recognizing overlapping determinants on glutamic acid decarboxylase (524-543)

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Active tolerance induction and prevention of autoimmune diabetes by immunogene therapy using recombinant adenoassociated virus expressing glutamic acid decarboxylase 65 peptide GAD(500-585).

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Autoreactive T cells in a partially humanized murine model of T1D.

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Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice

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Parameters influencing antigen-specific immunotherapy for Type 1 diabetes

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Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice.

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Nasal administration of CTB-insulin induces active tolerance against autoimmune diabetes in non-obese diabetic (NOD) mice

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Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes

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Gamma delta T cells as mediators of mucosal tolerance: the autoimmune diabetes model

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A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

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Identifiers

10.1016/J.VACCINE.2010.04.005

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31 January 2020

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