Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3 (Q84365414)

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4 February 2020

title

Interleukin-22 promotes human hepatocellular carcinoma by activation of STAT3 (English)

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4 February 2020

main subject

hepatocellular carcinoma

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Runqiu Jiang

1

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4 February 2020

Zhongming Tan

2

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4 February 2020

Lei Deng

3

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4 February 2020

Yun Chen

4

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4 February 2020

Yongxiang Xia

5

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4 February 2020

Yun Gao

6

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4 February 2020

Xuehao Wang

7

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4 February 2020

Beicheng Sun

8

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4 February 2020

language of work or name

English

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publication date

8 August 2011

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4 February 2020

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4 February 2020

volume

54

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issue

3

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4 February 2020

page(s)

900-909

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Hepatocellular carcinoma: epidemiology, risk factors, and screening

4 February 2020

cites work

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7 January 2021

STATs in cancer inflammation and immunity: a leading role for STAT3

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7 January 2021

Stats: transcriptional control and biological impact

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7 January 2021

Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment.

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7 January 2021

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

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7 January 2021

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

1 reference

7 January 2021

Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment

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7 January 2021

Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice

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7 January 2021

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

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7 January 2021

Th17 cells: a new fate for differentiating helper T cells

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7 January 2021

IL-17 can promote tumor growth through an IL-6-Stat3 signaling pathway

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7 January 2021

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

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7 January 2021

The STATs of cancer--new molecular targets come of age

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7 January 2021

Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production

1 reference

7 January 2021

Serum IL-6 levels and the risk for hepatocarcinogenesis in chronic hepatitis C patients: an analysis based on gender differences

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7 January 2021

Development in motion: helper T cells at work

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7 January 2021

Migration and function of Th17 cells

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7 January 2021

TH17 cells in development: an updated view of their molecular identity and genetic programming

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7 January 2021

The role of non-parenchymal cells in liver growth

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7 January 2021

Tumor-activated monocytes promote expansion of IL-17-producing CD8+ T cells in hepatocellular carcinoma patients

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7 January 2021

Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients.

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7 January 2021

Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10.

1 reference

7 January 2021

Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts.

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7 January 2021

Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma

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7 January 2021

A novel role for IL-22R1 as a driver of inflammation

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7 January 2021

Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation

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7 January 2021

High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer

1 reference

7 January 2021

Biology of interleukin-22.

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7 January 2021

Cloning and characterization of IL-10-related T cell-derived inducible factor (IL-TIF), a novel cytokine structurally related to IL-10 and inducible by IL-9.

1 reference

7 January 2021

IL-22 increases the innate immunity of tissues

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7 January 2021

IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis

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7 January 2021

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

1 reference

7 January 2021

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

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7 January 2021

IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease.

1 reference

7 January 2021

Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation

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7 January 2021

Interleukin 10 suppresses Th17 cytokines secreted by macrophages and T cells

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7 January 2021

The incidence, correlation with tumor-infiltrating inflammation, and prognosis of phosphorylated STAT3 expression in human gliomas.

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7 January 2021

yuDetecting the percent of peripheral blood mononuclear cells displaying p-STAT-3 in malignant glioma patients.

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7 January 2021

Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes

1 reference

7 January 2021

Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R

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7 January 2021

Structure of IL-22 bound to its high-affinity IL-22R1 chain

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7 January 2021

Identifiers

DOI

10.1002/HEP.24486

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4 February 2020

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