Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. (Q36691086)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

review article

1 reference

title

Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

author name string

Hua Yu

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

Drew Pardoll

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

publication date

1 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

23 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

page(s)

41-51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

23 December 2019

cites work

The Hallmarks of Cancer

1 reference

Cancer: what should be done?

31 March 2020

1 reference

The multistep nature of cancer

31 March 2020

1 reference

Cancer immunoediting: from immunosurveillance to tumor escape

31 March 2020

1 reference

Does the immune system see tumors as foreign or self?

31 March 2020

1 reference

Cancer immunotherapy: a treatment for the masses

31 March 2020

1 reference

Mechanisms and functional significance of tumour-induced dendritic-cell defects

31 March 2020

1 reference

Immunosuppressive networks in the tumour environment and their therapeutic relevance

31 March 2020

1 reference

Putting tumours in context

31 March 2020

1 reference

Tumour-educated macrophages promote tumour progression and metastasis

31 March 2020

1 reference

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

31 March 2020

1 reference

The role of STATs in transcriptional control and their impact on cellular function

31 March 2020

1 reference

The STATs of cancer--new molecular targets come of age

31 March 2020

1 reference

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

31 March 2020

1 reference

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

31 March 2020

1 reference

Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

31 March 2020

1 reference

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

31 March 2020

1 reference

Coordinated oncogenic transformation and inhibition of host immune responses by the PAX3-FKHR fusion oncoprotein

31 March 2020

1 reference

The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells

31 March 2020

1 reference

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

31 March 2020

1 reference

Gp130 and the interleukin-6 family of cytokines

31 March 2020

1 reference

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

31 March 2020

1 reference

Studies of IFN-induced transcriptional activation uncover the Jak-Stat pathway.

31 March 2020

1 reference

How cells respond to interferons

31 March 2020

1 reference

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

31 March 2020

1 reference

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation

31 March 2020

1 reference

Stat3 dimerization regulated by reversible acetylation of a single lysine residue

31 March 2020

1 reference

Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation

31 March 2020

1 reference

Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

31 March 2020

1 reference

Suppressors of cytokine signalling (SOCS) in the immune system

31 March 2020

1 reference

Suppressors of cytokine signaling and immunity

31 March 2020

1 reference

Regulation of gene-activation pathways by PIAS proteins in the immune system

31 March 2020

1 reference

Stat3 activation by Src induces specific gene regulation and is required for cell transformation

31 March 2020

1 reference

Stat3 activation is required for cellular transformation by v-src

31 March 2020

1 reference

31 March 2020

1 reference

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

31 March 2020

1 reference

Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor- mediated cell growth In vitro

31 March 2020

1 reference

The role of STATs in myeloid differentiation and leukemia

31 March 2020

1 reference

STAT signaling in the pathogenesis and treatment of leukemias

31 March 2020

1 reference

Targeting STAT3 affects melanoma on multiple fronts

31 March 2020

1 reference

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

31 March 2020

1 reference

Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis

31 March 2020

1 reference

Interleukin-6 promotes cervical tumor growth by VEGF-dependent angiogenesis via a STAT3 pathway

31 March 2020

1 reference

Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways

31 March 2020

1 reference

A novel activating function of c-Src and Stat3 on HGF transcription in mammary carcinoma cells

31 March 2020

1 reference

Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis.

31 March 2020

1 reference

Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C.

31 March 2020

1 reference

Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects

31 March 2020

1 reference

Tumour escape from immune surveillance through dendritic cell inactivation

31 March 2020

1 reference

Tolerogenic dendritic cells

31 March 2020

1 reference

Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.

31 March 2020

1 reference

IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation.

31 March 2020

1 reference

Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3.

31 March 2020

1 reference

A critical role for Stat3 signaling in immune tolerance

31 March 2020

1 reference

An oligonucleotide decoy for Stat3 activates the immune response of macrophages to breast cancer

31 March 2020

1 reference

Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

31 March 2020

1 reference

IFN-gamma controls the generation/activation of CD4+ CD25+ regulatory T cells in antitumor immune response.

31 March 2020

1 reference

Tumor-derived CD4(+)CD25(+) regulatory T cell suppression of dendritic cell function involves TGF-beta and IL-10

31 March 2020

1 reference

Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma

31 March 2020

1 reference

Regulatory T cells, tumour immunity and immunotherapy

31 March 2020

1 reference

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

31 March 2020

1 reference

Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma.

31 March 2020

1 reference

Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self

31 March 2020

1 reference

CD4+ CD25+ suppressor T cells: more questions than answers

31 March 2020

1 reference

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

31 March 2020

1 reference

Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

31 March 2020

1 reference

Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1

31 March 2020

1 reference

Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3

31 March 2020

1 reference

The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.

31 March 2020

1 reference

IL-2 regulates FOXP3 expression in human CD4+CD25+ regulatory T cells through a STAT-dependent mechanism and induces the expansion of these cells in vivo

31 March 2020

1 reference

Essential Role for STAT5 Signaling in CD25+CD4+ Regulatory T Cell Homeostasis and the Maintenance of Self-Tolerance

31 March 2020

1 reference

Loss of Tolerance and Autoimmunity Affecting Multiple Organs inSTAT5A/5B-Deficient Mice

31 March 2020

1 reference

Protein microarrays for multiplex analysis of signal transduction pathways

31 March 2020

1 reference

IL-2 overcomes the unresponsiveness but fails to reverse the regulatory function of antigen-induced T regulatory cells.

31 March 2020

1 reference

Distinct and overlapping roles of interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor CD8 T-cell responses

31 March 2020

1 reference

IL-23 promotes tumour incidence and growth

31 March 2020

1 reference

STAT3 regulates NF-kappaB recruitment to the IL-12p40 promoter in dendritic cells.

31 March 2020

1 reference

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

31 March 2020

1 reference

NF-kappaB: linking inflammation and immunity to cancer development and progression

31 March 2020

1 reference

Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer

31 March 2020

1 reference

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

31 March 2020

1 reference

Induced somatic inactivation of STAT3 in mice triggers the development of a fulminant form of enterocolitis

31 March 2020

1 reference

Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation

31 March 2020

1 reference

A novel platinum compound inhibits constitutive Stat3 signaling and induces cell cycle arrest and apoptosis of malignant cells

31 March 2020

1 reference

Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

31 March 2020

1 reference

The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation.

31 March 2020

1 reference

Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity

31 March 2020

1 reference

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

31 March 2020

1 reference

IDO expression by dendritic cells: tolerance and tryptophan catabolism

31 March 2020

1 reference

Cancer immunotherapy: moving beyond current vaccines

31 March 2020

1 reference

Spinning molecular immunology into successful immunotherapy

31 March 2020

1 reference

Immunotherapy: bewitched, bothered, and bewildered no more

31 March 2020

1 reference

Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody

31 March 2020

1 reference

Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway

31 March 2020

1 reference

IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells

31 March 2020

1 reference

Immunotherapy: target the stroma to hit the tumor

31 March 2020

1 reference

Tumor evasion of the immune system: inhibiting p38 MAPK signaling restores the function of dendritic cells in multiple myeloma

31 March 2020

1 reference

Stat3 regulates genes common to both wound healing and cancer

31 March 2020

1 reference

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

31 March 2020

1 reference

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target

31 March 2020

1 reference

Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.

31 March 2020

1 reference

Full oncogenic activities of v-Src are mediated by multiple signaling pathways. Ras as an essential mediator for cell survival.

31 March 2020

1 reference

STAT3 activation is required for Asp(816) mutant c-Kit induced tumorigenicity

31 March 2020

1 reference

Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis

31 March 2020

1 reference

Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling

31 March 2020

1 reference

Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors

31 March 2020

1 reference

Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression

31 March 2020

1 reference

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

31 March 2020

1 reference

Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma

31 March 2020

1 reference

Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma

31 March 2020

1 reference

Persistent activation of stat3 signaling induces survivin gene expression and confers resistance to apoptosis in human breast cancer cells

31 March 2020

1 reference

Role of Stat3 in regulating p53 expression and function

31 March 2020

1 reference

Co-operative effect of c-Src tyrosine kinase and Stat3 in activation of hepatocyte growth factor expression in mammary carcinoma cells

31 March 2020

1 reference

Activation of stat3 in human melanoma promotes brain metastasis.

31 March 2020

1 reference

STAT3 is a potential modulator of HIF-1-mediated VEGF expression in human renal carcinoma cells

31 March 2020

1 reference

Recruitment of STAT3 for production of IL-10 by colon carcinoma cells induced by macrophage-derived IL-6.

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI1995

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17186030%20AND%20SRC:MED&resulttype=core&format=json

release_mqlaa5m4ajazfofqotyklo5x2a

23 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mqlaa5m4ajazfofqotyklo5x2a

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference