Persistent hypocoagulability in patients with septic shock predicts greater hospital mortality: impact of impaired thrombin generation (Q84464759)

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6 February 2020

title

Persistent hypocoagulability in patients with septic shock predicts greater hospital mortality: impact of impaired thrombin generation (English)

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6 February 2020

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Paul B Massion

1

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6 February 2020

Pierre Peters

2

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6 February 2020

Didier Ledoux

3

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6 February 2020

Valentine Zimermann

4

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6 February 2020

Jean-Luc Canivet

5

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6 February 2020

Pierre P Massion

6

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6 February 2020

Pierre Damas

7

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6 February 2020

André Gothot

8

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6 February 2020

publication date

27 June 2012

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6 February 2020

published in

Intensive Care Medicine

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6 February 2020

volume

38

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6 February 2020

issue

8

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6 February 2020

page(s)

1326-1335

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Fibrin and fibrinolysis in infection and host defense

6 February 2020

cites work

1 reference

12 December 2020

Plasma markers of hypercoagulability in patients with serious infections and risk of septic shock

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New disseminated intravascular coagulation score: A useful tool to predict mortality in comparison with Acute Physiology and Chronic Health Evaluation II and Logistic Organ Dysfunction scores

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Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study.

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Thrombin generation in severe sepsis

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Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock

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12 December 2020

Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia

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12 December 2020

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

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12 December 2020

High thrombin generation measured in the presence of thrombomodulin is associated with an increased risk of recurrent venous thromboembolism

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Thrombelastography/thromboelastometry.

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12 December 2020

Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shock.

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12 December 2020

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Comparison of thrombelastometry with procalcitonin, interleukin 6, and C-reactive protein as diagnostic tests for severe sepsis in critical ill adults

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Prospective assessment of thrombin generation test for dose monitoring of bypassing therapy in hemophilia patients with inhibitors undergoing elective surgery.

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12 December 2020

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12 December 2020

Changing pattern of organ dysfunction in early human sepsis is related to mortality

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12 December 2020

Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: a prospective cohort study.

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12 December 2020

Simple coagulation tests improve survival prediction in patients with septic shock

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12 December 2020

Hypercoagulability in patients with type 2 diabetes mellitus detected by a thrombin generation assay

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12 December 2020

Efficacy and safety of recombinant human activated protein C for severe sepsis

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12 December 2020

Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death

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12 December 2020

Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies

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12 December 2020

High-dose antithrombin III in the treatment of severe sepsis in patients with a high risk of death: efficacy and safety

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12 December 2020

Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]

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12 December 2020

Coagulation in sepsis

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12 December 2020

The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation

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12 December 2020

Thrombin generation, a function test of the haemostatic-thrombotic system

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12 December 2020

Activation of the extrinsic coagulation pathway in patients with severe sepsis and septic shock

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12 December 2020

Four-day antithrombin therapy does not seem to attenuate hypercoagulability in patients suffering from sepsis

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12 December 2020

Global tests of haemostasis in critically ill patients with severe sepsis syndrome compared to controls

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12 December 2020

Thrombin generation in plasma of healthy adults and children: chromogenic versus fluorogenic thrombogram analysis

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12 December 2020

Comparison of thrombelastometry with simplified acute physiology score II and sequential organ failure assessment scores for the prediction of 30-day survival: a cohort study

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12 December 2020

What does it take to make the perfect clot?

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12 December 2020

Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial

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12 December 2020

10.1007/S00134-012-2620-2

Identifiers

DOI

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6 February 2020

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