Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice (Q85072476)

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14 February 2020

title

Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice (English)

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14 February 2020

9

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author name string

M Bajzer

1

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14 February 2020

M Olivieri

2

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14 February 2020

M K Haas

3

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14 February 2020

P T Pfluger

4

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I J Magrisso

5

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M T Foster

6

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M H Tschöp

7

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K A Krawczewski-Carhuatanta

8

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S Obici

10

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publication date

11 October 2011

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14 February 2020

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14 February 2020

volume

54

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issue

12

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page(s)

3121-3131

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https://scigraph.springernature.com/pub.10.1007/s00125-011-2302-6

14 February 2020

exact match

0 references

cites work

Brown adipose tissue activity controls triglyceride clearance.

1 reference

12 December 2020

Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats

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12 December 2020

The cannabinoid CB1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake

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12 December 2020

Efficacy and safety of the weight-loss drug rimonabant

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12 December 2020

Cold-activated brown adipose tissue in healthy men

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12 December 2020

CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity

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12 December 2020

Increased energy expenditure contributes more to the body weight-reducing effect of rimonabant than reduced food intake in candy-fed wistar rats

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12 December 2020

Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene

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12 December 2020

The effects of rimonabant on brown adipose tissue in rat: implications for energy expenditure.

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12 December 2020

Restoration of liver insulin signaling in Insr knockout mice fails to normalize hepatic insulin action

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12 December 2020

CB1 antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice

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12 December 2020

Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lep(ob)/Lep(ob) mice

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12 December 2020

Endogenous glucose production is inhibited by the adipose-derived protein Acrp30

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12 December 2020

Identification and importance of brown adipose tissue in adult humans

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12 December 2020

Effects on food intake and blood lipids of cannabinoid receptor 1 antagonist treatment in lean rats.

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12 December 2020

Surgical removal of brown fat results in rapid and complete compensation by other depots

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12 December 2020

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

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12 December 2020

CB(1) signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance

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12 December 2020

Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4.

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12 December 2020

The anti-obesity effect of rimonabant is associated with an improved serum lipid profile

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12 December 2020

Skeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. Relation to the insulin-mediated inhibition of hepatic glucose production

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12 December 2020

Differential activation of the sympathetic innervation of adipose tissues by melanocortin receptor stimulation.

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12 December 2020

Cold elicits the simultaneous induction of fatty acid synthesis and beta-oxidation in murine brown adipose tissue: prediction from differential gene expression and confirmation in vivo.

1 reference

12 December 2020

Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet

1 reference

12 December 2020

Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism

1 reference

12 December 2020

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

1 reference

12 December 2020

Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity

1 reference

12 December 2020

Adiponectin is required to mediate rimonabant-induced improvement of insulin sensitivity but not body weight loss in diet-induced obese mice

1 reference

12 December 2020

The endogenous cannabinoid system stimulates glucose uptake in human fat cells via phosphatidylinositol 3-kinase and calcium-dependent mechanisms

1 reference

12 December 2020

Transcriptional control of brown fat development

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12 December 2020

Activation of the peripheral endocannabinoid system in human obesity

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12 December 2020

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

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12 December 2020

Functional brown adipose tissue in healthy adults

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12 December 2020

Central endocannabinoid signaling regulates hepatic glucose production and systemic lipolysis

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12 December 2020

Sirt1 protects against high-fat diet-induced metabolic damage

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12 December 2020

Impaired insulin secretion and enhanced insulin sensitivity in cholecystokinin-deficient mice.

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12 December 2020

Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways

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12 December 2020

ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism

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12 December 2020

Quantitation of hepatic glucose fluxes and pathways of hepatic glycogen synthesis in conscious mice

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12 December 2020

Energy balance following sympathetic denervation of brown adipose tissue

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12 December 2020

Dietary obesity: brown fat denervation fails to alter development or recovery

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12 December 2020