Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo (Q87417401)

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10 March 2020

title

Knockdown of PTHR1 in osteosarcoma cells decreases invasion and growth and increases tumor differentiation in vivo (English)

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10 March 2020

4

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Kristi M Milley

5

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10 March 2020

Ross A. Dickins

11

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10 March 2020

Carl R Walkley

13

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10 March 2020

author name string

P W M Ho

1

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10 March 2020

A Goradia

2

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10 March 2020

M R Russell

3

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10 March 2020

E K Baker

6

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10 March 2020

J A Danks

7

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J L Slavin

8

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M Walia

9

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10 March 2020

B Crimeen-Irwin

10

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10 March 2020

T J Martin

12

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10 March 2020

publication date

21 July 2014

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10 March 2020

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10 March 2020

volume

34

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10 March 2020

issue

22

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page(s)

2922-2933

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A meta-analysis of osteosarcoma outcomes in the modern medical era

10 March 2020

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Twenty-five years of PTHrP progress: from cancer hormone to multifunctional cytokine

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Molecular properties of the PTH/PTHrP receptor

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Increased bone formation by prevention of osteoblast apoptosis with parathyroid hormone

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SOST is a target gene for PTH in bone

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On the interpretation of rat carcinogenicity studies for human PTH(1-34) and human PTH(1-84).

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Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma.

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Parathyroid hormone-responsive adenylate cyclase in induced transplantable osteogenic rat sarcoma

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Parathyroid hormone-responsive clonal cell lines from rat osteosarcoma

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Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

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Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

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IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma

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mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts

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Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice

31 March 2020

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Ontogeny of Phex/PHEX protein expression in mouse embryo and subcellular localization in osteoblasts

31 March 2020

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EphrinB2 regulation by PTH and PTHrP revealed by molecular profiling in differentiating osteoblasts

31 March 2020

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Parathyroid hormone is essential for normal fetal bone formation

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Osteoblast-derived PTHrP is a physiological regulator of bone formation

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Parathyroid hormone-related protein: immunohistochemical localization in cancers and in normal skin

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RANK-Fc inhibits malignancy via inhibiting ERK activation and evoking caspase-3-mediated anoikis in human osteosarcoma cells.

31 March 2020

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Regulation of cancer cell migration and bone metastasis by RANKL.

31 March 2020

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Homotypic RANK signaling differentially regulates proliferation, motility and cell survival in osteosarcoma and mammary epithelial cells.

31 March 2020

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Parathyroid hormone-related protein(1-34) regulates Phex expression in osteoblasts through the protein kinase A pathway

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Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death

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Opposing mitogenic and anti-mitogenic actions of parathyroid hormone-related protein in vascular smooth muscle cells: a critical role for nuclear targeting

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Cell-specific signal transduction of parathyroid hormone (PTH)-related protein through stably expressed recombinant PTH/PTHrP receptors in vascular smooth muscle cells

31 March 2020

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Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

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PTHrP and cell division: expression and localization of PTHrP in a keratinocyte cell line (HaCaT) during the cell cycle

31 March 2020

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12 December 2020

Radiation induced osteogenic sarcoma in the rat as a model of hormone-responsive differentiated cancer

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12 December 2020

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12 December 2020

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Identifiers

DOI

10.1038/ONC.2014.217

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25043296%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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