Enhanced liver gene transfer and evasion of preexisting humoral immunity with exosome-enveloped AAV vectors (Q89777435)

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8 April 2020

title

Enhanced liver gene transfer and evasion of preexisting humoral immunity with exosome-enveloped AAV vectors (English)

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8 April 2020

author name string

Amine Meliani

1

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8 April 2020

Florence Boisgerault

2

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8 April 2020

Zachary Fitzpatrick

3

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8 April 2020

Solenne Marmier

4

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8 April 2020

Christian Leborgne

5

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8 April 2020

Fanny Collaud

6

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8 April 2020

Marcelo Simon Sola

7

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8 April 2020

Severine Charles

8

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8 April 2020

Giuseppe Ronzitti

9

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8 April 2020

Alban Vignaud

10

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8 April 2020

Laetitia van Wittenberghe

11

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8 April 2020

Beatrice Marolleau

12

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8 April 2020

Fabienne Jouen

13

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8 April 2020

Sisareuth Tan

14

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8 April 2020

Olivier Boyer

15

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8 April 2020

Olivier Christophe

16

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8 April 2020

Alain R Brisson

17

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8 April 2020

Casey A Maguire

18

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8 April 2020

Federico Mingozzi

19

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8 April 2020

publication date

16 October 2017

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8 April 2020

volume

1

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8 April 2020

page(s)

2019-2031

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8 April 2020

issue

23

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Adeno-associated virus vectors can be efficiently produced without helper virus

8 April 2020

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Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer

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Long-term correction of inhibitor-prone hemophilia B dogs treated with liver-directed AAV2-mediated factor IX gene therapy

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AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells

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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

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A 10 patient case report on the impact of plasmapheresis upon neutralizing factors against adeno-associated virus (AAV) types 1, 2, 6, and 8.

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Neutralizing antibodies against adeno-associated virus examined prospectively in pediatric patients with hemophilia

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Adenovirus-associated virus vector-mediated gene transfer in hemophilia B

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Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B.

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Prevalence and pharmacological modulation of humoral immunity to AAV vectors in gene transfer to synovial tissue

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A pathogenic picornavirus acquires an envelope by hijacking cellular membranes

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12 December 2020

Immune responses to AAV vectors: overcoming barriers to successful gene therapy

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12 December 2020

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12 December 2020

Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies

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12 December 2020

AAV2/8 vectors purified from culture medium with a simple and rapid protocol transduce murine liver, muscle, and retina efficiently

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12 December 2020

Plasmapheresis eliminates the negative impact of AAV antibodies on microdystrophin gene expression following vascular delivery.

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Liposomal drug delivery: a versatile platform for challenging clinical applications.

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Promoterless gene targeting without nucleases ameliorates haemophilia B in mice.

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12 December 2020

Long-term safety and efficacy of factor IX gene therapy in hemophilia B.

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Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy.

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Long-term sex-biased correction of circulating propionic acidemia disease markers by adeno-associated virus vectors

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AAV capsid CD8+ T-cell epitopes are highly conserved across AAV serotypes

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Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper.

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Genotoxicity in Mice Following AAV Gene Delivery: A Safety Concern for Human Gene Therapy?

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TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity

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Phase I open label liver-directed gene therapy clinical trial for acute intermittent porphyria

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Identification and Characterization of 293T Cell-Derived Exosomes by Profiling the Protein, mRNA and MicroRNA Components

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Exosome-associated AAV vector as a robust and convenient neuroscience tool

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Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV.

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Autophagy determines efficiency of liver-directed gene therapy with adeno-associated viral vectors

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Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection

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Gene Therapy for Hemophilia.

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Exosomes and their Application in Biomedical Field: Difficulties and Advantages.

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10.1182/BLOODADVANCES.2017010181

Identifiers

DOI

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8 April 2020

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8 April 2020

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