Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic⁻Mediating Machinery (Q90639819)

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scientific article published on 27 July 2018

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English	Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic⁻Mediating Machinery	scientific article published on 27 July 2018

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30060527%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Combinational Proanthocyanidins and Resveratrol Synergistically Inhibit Human Breast Cancer Cells and Impact Epigenetic⁻Mediating Machinery (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30060527%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Trygve O. Tollefsbol

2

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15 April 2020

author name string

Yifeng Gao

1

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15 April 2020

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27 July 2018

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15 April 2020

International Journal of Molecular Sciences

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15 April 2020

19

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15 April 2020

8

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15 April 2020

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Creative Commons Attribution 4.0 International

27 July 2018

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April 2022 Public Data File from Crossref

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Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavonoids in the presence and absence of excess estrogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Capillary electrophoretic determination of resveratrol in wines

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency of caspase-3 in MCF7 cells blocks Bax-mediated nuclear fragmentation but not cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Estrogenic and antiestrogenic activities of flavonoid phytochemicals through estrogen receptor binding-dependent and -independent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between estrogen receptor-binding and estrogenic activities of environmental estrogens and suppression by flavonoids

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetics in human disease and prospects for epigenetic therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutritional flavonoids modulate estrogen receptor alpha signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grape seed proanthocyanidins induce apoptosis and inhibit metastasis of highly metastatic breast carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic potential of resveratrol: the in vivo evidence

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oenology: red wine procyanidins and vascular health

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mammalian epigenome

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grape seed proanthocyanidins promote apoptosis in human epidermoid carcinoma A431 cells through alterations in Cdki-Cdk-cyclin cascade, and caspase-3 activation via loss of mitochondrial membrane potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral squamous cell carcinoma proliferative phenotype is modulated by proanthocyanidins: a potential prevention and treatment alternative for oral cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Berry integrity and extraction of skin and seed proanthocyanidins during red wine fermentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LYR71, a derivative of trimeric resveratrol, inhibits tumorigenesis by blocking STAT3-mediated matrix metalloproteinase 9 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical versus clinical drug combination studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary grape seed proanthocyanidins inhibit 12-O-tetradecanoyl phorbol-13-acetate-caused skin tumor promotion in 7,12-dimethylbenz[a]anthracene-initiated mouse skin, which is associated with the inhibition of inflammatory responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grape seed proanthocyanidins inhibit the growth of human non-small cell lung cancer xenografts by targeting insulin-like growth factor binding protein-3, tumor cell proliferation, and angiogenic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cell proliferation by a resveratrol analog in human pancreatic and breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant-like effect of low molecular proanthocyanidin in mice: involvement of monoaminergic system

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol increases rate of apoptosis caused by purine analogues in malignant lymphocytes of chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Grape proanthocyanidin inhibit pancreatic cancer cell growth in vitro and in vivo through induction of apoptosis and by targeting the PI3K/Akt pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactivity of polymeric proanthocyanidins toward salivary proteins and their contribution to young red wine astringency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of Cisplatin-Mediated Apoptosis in Ovarian Cancer Cells through Potentiating G2/M Arrest and p21 Upregulation by Combinatorial Epigallocatechin Gallate and Sulforaphane

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-κB/STAT3 complex to its promoter in malignant lymphoid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytostatic and apoptotic effects of DNMT and HDAC inhibitors in endometrial cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol as a pan-HDAC inhibitor alters the acetylation status of histone [corrected] proteins in human-derived hepatoblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dentin biomodification potential depends on polyphenol source.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic-based combinatorial resveratrol and pterostilbene alters DNA damage response by affecting SIRT1 and DNMT enzyme expression, including SIRT1-dependent γ-H2AX and telomerase regulation in triple-negative breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combinatorial epigenetic mechanisms and efficacy of early breast cancer inhibition by nutritive botanicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-in-Cell Death Is Not Restricted by Caspase-3 Deficiency in MCF-7 Cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Novel Combination of Withaferin A and Sulforaphane Inhibits Epigenetic Machinery, Cellular Viability and Induces Apoptosis of Breast Cancer Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combinatorial bioactive botanicals re-sensitize tamoxifen treatment in ER-negative breast cancer via epigenetic reactivation of ERα expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of proanthocyanidins from red wine, and their inhibitory effects on melanin synthesis in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30060527

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/IJMS19082204

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30060527%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30060527%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30060527%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

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