Dengue Non-structural Protein 5 Polymerase Complexes With Promyelocytic Leukemia Protein (PML) Isoforms III and IV to Disrupt PML-Nuclear Bodies in Infected Cells (Q92923112)

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scientific article published on 13 August 2019

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English	Dengue Non-structural Protein 5 Polymerase Complexes With Promyelocytic Leukemia Protein (PML) Isoforms III and IV to Disrupt PML-Nuclear Bodies in Infected Cells	scientific article published on 13 August 2019

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2 May 2020

Dengue Non-structural Protein 5 Polymerase Complexes With Promyelocytic Leukemia Protein (PML) Isoforms III and IV to Disrupt PML-Nuclear Bodies in Infected Cells (English)

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2 May 2020

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dengue virus protein NS5

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modulation by virus of host process

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Federico Giovannoni

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Federico Giovannoni

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María Fatima Ladelfa

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Martin Monte

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David A Jans

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Peter Hemmerich

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Cybele García

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13 August 2019

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Frontiers in Cellular and Infection Microbiology

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13 August 2019

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Multimodal Light Microscopy Approaches to Reveal Structural and Functional Properties of Promyelocytic Leukemia Nuclear Bodies.

1 reference

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Nucleocytoplasmic Trafficking of Dengue Non-structural Protein 5 as a Target for Antivirals.

1 reference

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Immune Response to Dengue and Zika

1 reference

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11 February 2021

Strand-like structures and the nonstructural proteins 5, 3 and 1 are present in the nucleus of mosquito cells infected with dengue virus

1 reference

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Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection.

1 reference

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The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing

1 reference

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Promyelocytic leukemia protein isoform II inhibits infection by human adenovirus type 5 through effects on HSP70 and the interferon response.

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Dynamic Nucleolar Targeting of Dengue Virus Polymerase NS5 in Response to Extracellular pH

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Emerging Role of PML Nuclear Bodies in Innate Immune Signaling

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A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity

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SnapShot: antiviral restriction factors

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Respiratory virus modulation of host nucleocytoplasmic transport; target for therapeutic intervention?

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11 February 2021

Cellular promyelocytic leukemia protein is an important dengue virus restriction factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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A nuclear transport inhibitor that modulates the unfolded protein response and provides in vivo protection against lethal dengue virus infection.

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An evolutionary screen highlights canonical and noncanonical candidate antiviral genes within the primate TRIM gene family

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Nuclear localization of dengue virus (DENV) 1-4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin.

1 reference

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11 February 2021

Differential Roles of PML Isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

11 February 2021

The global distribution and burden of dengue

1 reference

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11 February 2021

Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling

1 reference

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PML promotes MHC class II gene expression by stabilizing the class II transactivator

1 reference

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11 February 2021

Evolutionary conflicts between viruses and restriction factors shape immunity

1 reference

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1 reference

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11 February 2021

Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

11 February 2021

Promyelocytic leukemia isoform IV confers resistance to encephalomyocarditis virus via the sequestration of 3D polymerase in nuclear bodies

1 reference

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Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virus

1 reference

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Role of promyelocytic leukemia protein in host antiviral defense

1 reference

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11 February 2021

SUMOylation promotes PML degradation during encephalomyocarditis virus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

11 February 2021

Assembly dynamics of PML nuclear bodies in living cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

11 February 2021

A manually curated network of the PML nuclear body interactome reveals an important role for PML-NBs in SUMOylation dynamics

1 reference

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Dengue Virus Capsid Protein Usurps Lipid Droplets for Viral Particle Formation

1 reference

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11 February 2021

Composition and three-dimensional architecture of the dengue virus replication and assembly sites

1 reference

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11 February 2021

CRM1-mediated Nuclear Export of Dengue Virus RNA Polymerase NS5 Modulates Interleukin-8 Induction and Virus Production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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NS5 of dengue virus mediates STAT2 binding and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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Dynamics of component exchange at PML nuclear bodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

11 February 2021

Multiple regions in dengue virus capsid protein contribute to nuclear localization during virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection.

1 reference

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Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion

1 reference

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1 reference

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PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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HPV E6 proteins interact with specific PML isoforms and allow distinctions to be made between different POD structures.

1 reference

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The interaction of cytoplasmic RNA viruses with the nucleus

1 reference

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The interaction of animal cytoplasmic RNA viruses with the nucleus to facilitate replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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Rabies virus P and small P products interact directly with PML and reorganize PML nuclear bodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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PML protein isoforms and the RBCC/TRIM motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

11 February 2021

Two RING finger proteins, the oncoprotein PML and the arenavirus Z protein, colocalize with the nuclear fraction of the ribosomal P proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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Detection of dengue 4 virus core protein in the nucleus. I. A monoclonal antibody to dengue 4 virus reacts with the antigen in the nucleus and cytoplasm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6701172

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Alternative splicing of PML transcripts predicts coexpression of several carboxy-terminally different protein isoforms

1 reference

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11 February 2021

Identifiers

10.3389/FCIMB.2019.00284

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2 May 2020

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2 May 2020

PubMed publication ID

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2 May 2020

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