Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program (Q93105631)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31484833%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

title

Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program (English)

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3 May 2020

1

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3 May 2020

Galen C Cheng

3

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3 May 2020

Ahmet Hoke

6

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3 May 2020

Aaron DiAntonio

8

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3 May 2020

author name string

Ryan A Doan

2

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3 May 2020

Aysel Cetinkaya-Fisgin

4

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3 May 2020

Shay X Huang

5

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3 May 2020

Jeffrey Milbrandt

7

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3 May 2020

publication date

5 September 2019

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3 May 2020

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3 May 2020

volume

4

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3 May 2020

issue

17

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describes a project that uses

3 May 2020

ImageJ

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11 June 2022

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based on heuristic

inferred from PubMed Central ID database lookup

cites work

A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death

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Axon degeneration: mechanistic insights lead to therapeutic opportunities for the prevention and treatment of peripheral neuropathy

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Gene therapy targeting SARM1 blocks pathological axon degeneration in mice

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Pharmacological bypass of NAD salvage pathway protects neurons from chemotherapy-induced degeneration

11 February 2021

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Palmitoylation enables MAPK-dependent proteostasis of axon survival factors

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Role of SARM1 and DR6 in retinal ganglion cell axonal and somal degeneration following axonal injury.

11 February 2021

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Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration

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11 February 2021

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Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration

11 February 2021

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Deletion of Sarm1 gene is neuroprotective in two models of peripheral neuropathy

11 February 2021

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Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats

11 February 2021

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The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration.

11 February 2021

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MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.

11 February 2021

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Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice.

11 February 2021

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NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

11 February 2021

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Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

11 February 2021

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Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice

11 February 2021

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Axon degeneration: context defines distinct pathways

11 February 2021

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Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling.

11 February 2021

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Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism

11 February 2021

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11 February 2021

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SARM1 activation triggers axon degeneration locally via NAD⁺ destruction

11 February 2021

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Absence of SARM1 rescues development and survival of NMNAT2-deficient axons

11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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11 February 2021

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Evaluation of tubulin polymerization and chronic inhibition of proteasome as citotoxicity mechanisms in bortezomib-induced peripheral neuropathy.

11 February 2021

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Apoptotic cell death and altered calcium homeostasis caused by frataxin depletion in dorsal root ganglia neurons can be prevented by BH4 domain of Bcl-xL protein

11 February 2021

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11 February 2021

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11 February 2021

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Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy

11 February 2021

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Persistent chemoneuropathy in patients receiving the plant alkaloids paclitaxel and vincristine

11 February 2021

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A caspase cascade regulating developmental axon degeneration

11 February 2021

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dSarm/Sarm1 is required for activation of an injury-induced axon death pathway

11 February 2021

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A new model to study spinal muscular atrophy: Neurite degeneration and cell death is counteracted by BCL-XL Overexpression in motoneurons

11 February 2021

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Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway

11 February 2021

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Neurophysiological and neuropathological characterization of new murine models of chemotherapy-induced chronic peripheral neuropathies.

11 February 2021

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Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

11 February 2021

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Proteasome inhibition activates the mitochondrial pathway of apoptosis in human CD4+ T cells

11 February 2021

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The Immune Adaptor Molecule SARM Modulates Tumor Necrosis Factor Alpha Production and Microglia Activation in the Brainstem and Restricts West Nile Virus Pathogenesis

11 February 2021

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Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy

11 February 2021

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Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide

11 February 2021

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A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration

11 February 2021

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6777905

A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells

11 February 2021

1 reference

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Quantitative Sensory Findings in Patients With Bortezomib-Induced Pain

11 February 2021

1 reference

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Erythropoietin protects sensory axons against paclitaxel-induced distal degeneration

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6777905

Evidence for direct axonal toxicity in vincristine neuropathy.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6777905

Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6777905

Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6777905

Evidence that Wallerian degeneration and localized axon degeneration induced by local neurotrophin deprivation do not involve caspases

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6777905

Evolution of neuropathy and myopathy during intensive vincristine/corticosteroid chemotherapy for non-hodgkin's lymphoma

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6777905

10.1172/JCI.INSIGHT.129920

11 February 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31484833%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31484833%20AND%20SRC:MED&resulttype=core&format=json

3 May 2020

PubMed publication ID

31484833

1 reference