Drug development in targeting ion channels for brain edema (Q98778662)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

30 August 2020

title

Drug development in targeting ion channels for brain edema (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

30 August 2020

author name string

Zheng-Wei Luo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

30 August 2020

Andrea Ovcjak

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

30 August 2020

Raymond Wong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

30 August 2020

Bao-Xue Yang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

30 August 2020

Zhong-Ping Feng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

30 August 2020

Hong-Shuo Sun

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

30 August 2020

publication date

27 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

Acta Pharmacologica Sinica

30 August 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32855530%20AND%20SRC:MED&resulttype=core&format=json

Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments

30 August 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Pathophysiological aspects of brain edema

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The cellular mechanisms of neuronal swelling underlying cytotoxic edema

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Mortality of space-occupying ('malignant') middle cerebral artery infarction under conservative intensive care

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

'Malignant' middle cerebral artery territory infarction: clinical course and prognostic signs

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Stroke treatment: time is brain.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Ischaemic brain oedema

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Drowning stars: reassessing the role of astrocytes in brain edema

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Hypertonic saline and mannitol therapy in critical care neurology

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Hypertonic saline: first-line therapy for cerebral edema?

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Decompressive Bifrontal Craniectomy in the Treatment of Severe Refractory Posttraumatic Cerebral Edema

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Pathophysiology and treatment of cerebral edema in traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Molecular pathophysiology of cerebral edema

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Cytotoxic edema: mechanisms of pathological cell swelling

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Brain tissue sodium is a ticking clock telling time after arterial occlusion in rat focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Brain edema during ischemia and after restoration of blood flow. Measurement of water, sodium, potassium content and plasma protein permeability

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Cerebrospinal fluid influx drives acute ischemic tissue swelling

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 reduces infarct size

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

VEGF and flt. Expression time kinetics in rat brain infarct

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Attenuation of intracerebral hemorrhage and thrombin-induced brain edema by overexpression of interleukin-1 receptor antagonist

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Substance P in traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Excitotoxicity and stroke: identifying novel targets for neuroprotection.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Glutamate and GABA imbalance following traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Potassium homeostasis in the ischemic brain.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Pathobiology of ischaemic stroke: an integrated view

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Emerging mechanisms of disrupted cellular signaling in brain ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Kir6.2-containing ATP-sensitive potassium channels protect cortical neurons from ischemic/anoxic injury in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Enhanced neuronal damage after ischemic insults in mice lacking Kir6.2-containing ATP-sensitive K+ channels

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Neuroprotection in ischemia: blocking calcium-permeable acid-sensing ion channels.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Blockade of the swelling-induced chloride current attenuates the mouse neonatal hypoxic-ischemic brain injury in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Ischemia opens neuronal gap junction hemichannels

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The molecular basis of water transport in the brain

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Temporary loss of perivascular aquaporin-4 in neocortex after transient middle cerebral artery occlusion in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Loss of astrocyte polarization upon transient focal brain ischemia as a possible mechanism to counteract early edema formation

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Aquaporin water channels--from atomic structure to clinical medicine

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Physiological evidence that pyramidal neurons lack functional water channels

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Delayed increase of astrocytic aquaporin 4 after juvenile traumatic brain injury: possible role in edema resolution?

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Induction of aquaporin-4 water channel mRNA after focal cerebral ischemia in rat.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Heterogeneous responses of aquaporin-4 in oedema formation in a replicated severe traumatic brain injury model in rats

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Time course of aquaporin expression after transient focal cerebral ischemia in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Improved long-term outcome after transient cerebral ischemia in aquaporin-4 knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Neuroprotective effect of aquaporin-4 deficiency in a mouse model of severe global cerebral ischemia produced by transient 4-vessel occlusion.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Heterogeneity of aquaporin-4 localization and expression after focal cerebral ischemia underlies differences in white versus grey matter swelling

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Expression of water channel mRNA following cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Aggravated chronic brain injury after focal cerebral ischemia in aquaporin-4-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Deletion of aquaporin-4 is neuroprotective during the acute stage of micro traumatic brain injury in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice following Controlled Cortical Impact Brain Injury.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Posttraumatic reduction of edema with aquaporin-4 RNA interference improves acute and chronic functional recovery

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Decreased hemispheric Aquaporin-4 is linked to evolving brain edema following controlled cortical impact injury in rats.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Enhanced expression of aquaporin 4 in human brain with infarction

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Increased expression of aquaporin-4 in human traumatic brain injury and brain tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Aquaporin-4 distribution in control and stressed astrocytes in culture and in the cerebrospinal fluid of patients with traumatic brain injuries

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Three distinct roles of aquaporin-4 in brain function revealed by knockout mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Aquaporin-4 deficiency impairs synaptic plasticity and associative fear memory in the lateral amygdala: involvement of downregulation of glutamate transporter-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Aquaporin-4 independent Kir4.1 K+ channel function in brain glial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Identification of aquaporin 4 inhibitors using in vitro and in silico methods

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Acetazolamide reversibly inhibits water conduction by aquaporin-4.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Lack of aquaporin-4 water transport inhibition by antiepileptics and arylsulfonamides

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Acetazolamide Treatment Prevents Redistribution of Astrocyte Aquaporin 4 after Murine Traumatic Brain Injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Pretreatment with a novel aquaporin 4 inhibitor, TGN-020, significantly reduces ischemic cerebral edema

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Inhibition of Aquaporin-4 Improves the Outcome of Ischaemic Stroke and Modulates Brain Paravascular Drainage Pathways.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Two-dimensional crystal structure of aquaporin-4 bound to the inhibitor acetazolamide

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Operation Brain Trauma Therapy: 2016 Update.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Na(+)-K (+)-2Cl (-) cotransport inhibitor attenuates cerebral edema following experimental stroke via the perivascular pool of aquaporin-4.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Inhibition of aquaporin-1 and aquaporin-4 water permeability by a derivative of the loop diuretic bumetanide acting at an internal pore-occluding binding site

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Bumetanide inhibition of the blood-brain barrier Na-K-Cl cotransporter reduces edema formation in the rat middle cerebral artery occlusion model of stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The protein kinase C activator phorbol myristate acetate decreases brain edema by aquaporin 4 downregulation after middle cerebral artery occlusion in the rat

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The modulation of aquaporin-4 by using PKC-activator (phorbol myristate acetate) and V1a receptor antagonist (SR49059) following middle cerebral artery occlusion/reperfusion in the rat.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Selective vasopressin-1a receptor antagonist prevents brain edema, reduces astrocytic cell swelling and GFAP, V1aR and AQP4 expression after focal traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Aquaporin 4 and neuromyelitis optica

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Cell swelling and a nonselective cation channel regulated by internal Ca2+ and ATP in native reactive astrocytes from adult rat brain.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Review. SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Glibenclamide Reduces Hippocampal Injury and Preserves Rapid Spatial Learning in a Model of Traumatic Brain Injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Sulfonylurea Receptor-1: A Novel Biomarker for Cerebral Edema in Severe Traumatic Brain Injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

ABCC8 Single Nucleotide Polymorphisms are Associated with Cerebral Edema in Severe TBI.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

SUR1-TRPM4 channels, not KATP, mediate brain swelling following cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K(ATP) channels

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Sulfonylurea receptor 1 in central nervous system injury: a focused review

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

SUR1-TRPM4 and AQP4 form a heteromultimeric complex that amplifies ion/water osmotic coupling and drives astrocyte swelling.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Glibenclamide reduces secondary brain damage after experimental traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Glyburide is associated with attenuated vasogenic edema in stroke patients.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Long-Term Outcomes in Patients Aged ≤70 Years With Intravenous Glyburide From the Phase II GAMES-RP Study of Large Hemispheric Infarction: An Exploratory Analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Neuronal K(ATP) channels mediate hypoxic preconditioning and reduce subsequent neonatal hypoxic-ischemic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Cerebrovascular Safety of Sulfonylureas: The Role of KATP Channels in Neuroprotection and the Risk of Stroke in Patients With Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Electrically silent cotransport on Na+, K+ and Cl- in Ehrlich cells

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The role of Na-K-Cl co-transporter in cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Structure and mechanism of the cation-chloride cotransporter NKCC1

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Regulation of Na(+)-K(+)-Cl(-) cotransporter in primary astrocytes by dibutyryl cAMP and high [K(+)](o).

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Changes and effects of plasma arginine vasopressin in traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Na(+)-dependent chloride transporter (NKCC1)-null mice exhibit less gray and white matter damage after focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Contribution of Na(+)-K(+)-Cl(-) cotransporter to high-[K(+)](o)- induced swelling and EAA release in astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Astrocytes from Na(+)-K(+)-Cl(-) cotransporter-null mice exhibit absence of swelling and decrease in EAA release

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Moderate-to-severe ischemic conditions increase activity and phosphorylation of the cerebral microvascular endothelial cell Na+-K+-Cl- cotransporter.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Na+-K+-Cl- cotransporter in rat focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Transient receptor potential vanilloid type 4 channels mediate Na-K-Cl-co-transporter-induced brain edema after traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Bumetanide administration attenuated traumatic brain injury through IL-1 overexpression

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium-potassium-chloride-cotransporter human variants hNKCC1A and hNKCC1B.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

A novel prodrug-based strategy to increase effects of bumetanide in epilepsy

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The bumetanide prodrug BUM5, but not bumetanide, potentiates the antiseizure effect of phenobarbital in adult epileptic mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

A Novel Na+-K+-Cl- Cotransporter 1 Inhibitor STS66* Reduces Brain Damage in Mice After Ischemic Stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Erythrocyte K-Cl cotransport: properties and regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Volume-sensitive KCI cotransport associated with human cervical carcinogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Relative contribution of chloride channels and transporters to regulatory volume decrease in human glioma cells

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

KCC2a expression in a human fetal lens epithelial cell line

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The potassium-chloride cotransporter 2 promotes cervical cancer cell migration and invasion by an ion transport-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Roles of the cation-chloride cotransporters in neurological disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Altered expression of regulators of the cortical chloride transporters NKCC1 and KCC2 in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

KCC2, epileptiform synchronization, and epileptic disorders

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Trans-synaptic shift in anion gradient in spinal lamina I neurons as a mechanism of neuropathic pain

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Changes in intracellular chloride after oxygen-glucose deprivation of the adult hippocampal slice: effect of diazepam.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Downregulation of potassium chloride cotransporter KCC2 after transient focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Brain injury impairs dentate gyrus inhibitory efficacy

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Melatonin attenuates neuronal apoptosis through up-regulation of K(+) -Cl(-) cotransporter KCC2 expression following traumatic brain injury in rats.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by calcium-activated protease calpain.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl- co-transporter KCC2.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Posttraumatic GABA(A)-mediated [Ca2+]i increase is essential for the induction of brain-derived neurotrophic factor-dependent survival of mature central neurons

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Hyperexcitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Behavioural phenotypes of hypomorphic KCC2-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Further optimization of the K-Cl cotransporter KCC2 antagonist ML077: development of a highly selective and more potent in vitro probe

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Volume-regulated anion channel--a frenemy within the brain

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Ca2+ sensitivity of volume-regulatory K+ and Cl- channels in cultured human epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

SWELL1, a plasma membrane protein, is an essential component of volume-regulated anion channel

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Structure of a volume-regulated anion channel of the LRRC8 family

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Volume regulated anion channel currents of rat hippocampal neurons and their contribution to oxygen-and-glucose deprivation induced neuronal death

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Glutamate-Releasing SWELL1 Channel in Astrocytes Modulates Synaptic Transmission and Promotes Brain Damage in Stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Volume-regulated anion channels are the predominant contributors to release of excitatory amino acids in the ischemic cortical penumbra

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

ATP potently modulates anion channel-mediated excitatory amino acid release from cultured astrocytes.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

DCPIB, a specific inhibitor of volume regulated anion channels (VRACs), reduces infarct size in MCAo and the release of glutamate in the ischemic cortical penumbra

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

DCPIB, the proposed selective blocker of volume-regulated anion channels, inhibits several glutamate transport pathways in glial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

TMEM16A confers receptor-activated calcium-dependent chloride conductance

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Expression cloning of TMEM16A as a calcium-activated chloride channel subunit

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Anoctamin 2/TMEM16B: a calcium-activated chloride channel in olfactory transduction

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Recent advances in TMEM16A: Structure, function, and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

X-ray structure of a calcium-activated TMEM16 lipid scramblase

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Cryo-EM structures of the TMEM16A calcium-activated chloride channel.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Hypoxia augments the calcium-activated chloride current carried by anoctamin-1 in cardiac vascular endothelial cells of neonatal mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistance

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

TMEM16A Inhibition Preserves Blood-Brain Barrier Integrity After Ischemic Stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

New selective inhibitors of calcium-activated chloride channels - T16A(inh) -A01, CaCC(inh) -A01 and MONNA - what do they inhibit?

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Sodium Tanshinone IIA Sulfonate Enhances Effectiveness Rt-PA Treatment in Acute Ischemic Stroke Patients Associated with Ameliorating Blood-Brain Barrier Damage

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Molecular Structure of the Human CFTR Ion Channel.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Neurologic complications following lung transplantation

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Cystic fibrosis patients with and without central nervous system complications following lung transplantation

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

CFTR prevents neuronal apoptosis following cerebral ischemia reperfusion via regulating mitochondrial oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Chloride transport-driven alveolar fluid secretion is a major contributor to cardiogenic lung edema

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Involvement of cystic fibrosis transmembrane conductance regulator in infection-induced edema.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

CFTR Therapeutics Normalize Cerebral Perfusion Deficits in Mouse Models of Heart Failure and Subarachnoid Hemorrhage

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

1 reference

7 January 2021

Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure-activity analysis, and in vivo efficacy

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Comparative Effects of Chloride Channel Inhibitors on LRRC8/VRAC-Mediated Chloride Conductance.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

ClC Channels and Transporters: Structure, Physiological Functions, and Implications in Human Chloride Channelopathies

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Structure and pharmacology of swelling-sensitive chloride channels, I(Cl,swell).

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

ClC-2 chloride channels contribute to HTC cell volume homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Leukoencephalopathy upon disruption of the chloride channel ClC-2.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Brain white matter oedema due to ClC-2 chloride channel deficiency: an observational analytical study

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Molecular identification of a volume-regulated chloride channel

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Chloride channels in stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The role of ClC-3 in volume-activated chloride currents and volume regulation in bovine epithelial cells demonstrated by antisense inhibition

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

ClC-3 chloride channel prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through mitochondria dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Plasmalemmal Na+/Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Structural Features of Ion Transport and Allosteric Regulation in Sodium-Calcium Exchanger (NCX) Proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Ca2+ regulation in the Na+/Ca2+ exchanger involves two markedly different Ca2+ sensors

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Steady-state and dynamic properties of cardiac sodium-calcium exchange. Secondary modulation by cytoplasmic calcium and ATP

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Multiple transport modes of the cardiac Na+/Ca2+ exchanger.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Evidence for a protective role played by the Na+/Ca2+ exchanger in cerebral ischemia induced by middle cerebral artery occlusion in male rats

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The role of Na+/Ca2+ exchanger subtypes in neuronal ischemic injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Mechanical strain injury increases intracellular sodium and reverses Na+/Ca2+ exchange in cortical astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Two sodium/calcium exchanger gene products, NCX1 and NCX3, play a major role in the development of permanent focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Na(+)/Ca(2+) exchanger 2 is neuroprotective by exporting Ca(2+) during a transient focal cerebral ischemia in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Transient Oxygen/Glucose Deprivation Causes a Delayed Loss of Mitochondria and Increases Spontaneous Calcium Signaling in Astrocytic Processes

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

KB-R7943 inhibits store-operated Ca(2+) entry in cultured neurons and astrocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Molecular determinants of Na+/Ca2+ exchange (NCX1) inhibition by SEA0400.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

The selective Na+-Ca2+ exchange inhibitor attenuates brain edema after radiofrequency lesion in rats

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Neuronal NCX1 overexpression induces stroke resistance while knockout induces vulnerability via Akt

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Astrocyte-neuron lactate transport is required for long-term memory formation

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Neurons rely on glucose rather than astrocytic lactate during stimulation

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Glucose transporter proteins in brain: delivery of glucose to neurons and glia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Blood-brain barrier glucose transporter is asymmetrically distributed on brain capillary endothelial lumenal and ablumenal membranes: an electron microscopic immunogold study

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Functional expression of SGLTs in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

A functional role for sodium-dependent glucose transport across the blood-brain barrier during oxygen glucose deprivation

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Regional distribution of SGLT activity in rat brain in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

RS1 (Rsc1A1) deficiency limits cerebral SGLT1 expression and delays brain damage after experimental traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Spatiotemporal uptake characteristics of [18]F-2-fluoro-2-deoxy-D-glucose in a rat middle cerebral artery occlusion model

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Imaging of a clinically relevant stroke model: glucose hypermetabolism revisited.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Predictors for Cerebral Edema in Acute Ischemic Stroke Treated With Intravenous Thrombolysis.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Elevated blood glucose is associated with aggravated brain edema in acute stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Validation of sodium/glucose cotransporter proteins in human brain as a potential marker for temporal narrowing of the trauma formation

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Heteromeric acid-sensing ion channels (ASICs) composed of ASIC2b and ASIC1a display novel channel properties and contribute to acidosis-induced neuronal death

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Structure and activity of the acid-sensing ion channels

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Acid-sensing ion channels (ASICs): pharmacology and implication in pain

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Loss of Acid sensing ion channel-1a and bicarbonate administration attenuate the severity of traumatic brain injury

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neurons

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Extracellular acidosis increases neuronal cell calcium by activating acid-sensing ion channel 1a

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Extracellular spermine exacerbates ischemic neuronal injury through sensitization of ASIC1a channels to extracellular acidosis

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Prolonged activation of ASIC1a and the time window for neuroprotection in cerebral ischaemia

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Differential hippocampal protection when blocking intracellular sodium and calcium entry during traumatic brain injury in rats

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Increased tolerance to oxygen and glucose deprivation in astrocytes from Na(+)/H(+) exchanger isoform 1 null mice

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Decreased neuronal death in Na+/H+ exchanger isoform 1-null mice after in vitro and in vivo ischemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Selective knockout of astrocytic Na+ /H+ exchanger isoform 1 reduces astrogliosis, BBB damage, infarction, and improves neurological function after ischemic stroke

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021

Intravenous HOE-642 reduces brain edema and Na uptake in the rat permanent middle cerebral artery occlusion model of stroke: evidence for participation of the blood-brain barrier Na/H exchanger

1 reference

https://api.crossref.org/works/10.1038%2FS41401-020-00503-5

7 January 2021