NLRP3: A Novel Mediator in Cardiovascular Disease. (Q55050955)

http://europepmc.org/abstract/PMC/5911339

16 June 2018

8 references

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24 January 2021

NLRP3: A Novel Mediator in Cardiovascular Disease. (English)

1 reference

http://europepmc.org/abstract/PMC/5911339

16 June 2018

main subject

cardiovascular disease

6 references

13 March 2019

14 March 2019

24 March 2019

17 June 2019

16 November 2019

20 November 2019

complications of diabetes mellitus

8 references

13 March 2019

14 March 2019

24 March 2019

17 June 2019

16 November 2019

20 November 2019

23 January 2021

24 January 2021

6 references

13 March 2019

14 March 2019

24 March 2019

17 June 2019

16 November 2019

20 November 2019

macromolecular substances

1 reference

16 November 2019

1 reference

20 November 2019

intracellular signaling peptides and proteins

1 reference

PubMed

NLR family pyrin domain containing 3

23 January 2021

1 reference

24 January 2021

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Yanfang Chen

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Wenyi Zhou

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Chunyuan Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Zhiheng Chen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Lin Liu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Jie Jiang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Zhixiang Wu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

8 April 2018

9 references

http://europepmc.org/abstract/PMC/5911339

16 June 2018

13 March 2019

14 March 2019

24 March 2019

17 June 2019

16 November 2019

20 November 2019

23 January 2021

24 January 2021

Journal of Immunology Research

9 references

13 March 2019

14 March 2019

24 March 2019

17 June 2019

16 November 2019

20 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

23 January 2021

24 January 2021

2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

5702103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

1 June 2020

copyright license

8 references

13 March 2019

14 March 2019

24 March 2019

17 June 2019

16 November 2019

20 November 2019

23 January 2021

on focus list of Wikimedia project

24 January 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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1 reference

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Activation of NLRP3 inflammasomes contributes to hyperhomocysteinemia-aggravated inflammation and atherosclerosis in apoE-deficient mice

16 June 2018

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MicroRNA-9 Inhibits NLRP3 Inflammasome Activation in Human Atherosclerosis Inflammation Cell Models through the JAK1/STAT Signaling Pathway

16 June 2018

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Role of NLRP3 Inflammasomes in Atherosclerosis

16 June 2018

1 reference

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Triptolide attenuates pressure overload-induced myocardial remodeling in mice via the inhibition of NLRP3 inflammasome expression

16 June 2018

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What do we know about the inflammasome in humans?

16 June 2018

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PEDF Inhibits the Activation of NLRP3 Inflammasome in Hypoxia Cardiomyocytes through PEDF Receptor/Phospholipase A2.

16 June 2018

1 reference

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NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular Damage

16 June 2018

1 reference

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PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation

16 June 2018

1 reference

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Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis

16 June 2018

1 reference

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NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

NLRP3 inflammasome activation during myocardial ischemia reperfusion is cardioprotective

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

NOD-Like Receptors in Infection, Immunity, and Diseases

16 June 2018

1 reference

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Anti-Inflammatory Treatment With Colchicine in Acute Myocardial Infarction: A Pilot Study

16 June 2018

1 reference

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Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr(-/-) mice

16 June 2018

1 reference

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P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Anti-inflammatory and antiatherogenic effects of the NLRP3 inflammasome inhibitor arglabin in ApoE2.Ki mice fed a high-fat diet

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Endothelial Nlrp3 inflammasome activation associated with lysosomal destabilization during coronary arteritis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

NLRP3 and downstream cytokine expression elevated in the monocytes of patients with coronary artery disease

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Involvement of NLRP3 inflammasome in CVB3-induced viral myocarditis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Cardiac fibroblasts contribute to myocardial dysfunction in mice with sepsis: the role of NLRP3 inflammasome activation

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Endothelial dysfunction: the role of sterol regulatory element-binding protein-induced NOD-like receptor family pyrin domain-containing protein 3 inflammasome in atherosclerosis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

NLRP3 gene silencing ameliorates diabetic cardiomyopathy in a type 2 diabetes rat model

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

α7 nicotinic acetylcholine receptor signaling inhibits inflammasome activation by preventing mitochondrial DNA release

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

LOX-1, mtDNA damage, and NLRP3 inflammasome activation in macrophages: implications in atherogenesis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia-reperfusion in the mouse

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Biochemical and structural aspects of the ATP-binding domain in inflammasome-forming human NLRP proteins

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

NLRP3 inflammasome activation in coronary artery disease: results from prospective and randomized study of treatment with atorvastatin or rosuvastatin

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Inflammation in atherosclerosis

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Cryopyrin activates the inflammasome in response to toxins and ATP

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

The inflammatory response in myocardial infarction

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Effects of chronically increased VEGF-A on the aging heart.

16 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

The NLRP3 inflammasome in acute myocardial infarction

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

NLRP3 inflammasome pathways in atherosclerosis.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Statin regulates NLRP1 inflammasome expression through SREBP1: A novel anti-atherosclerotic mechanism.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Statin protects the heart against ischemia-reperfusion injury via inhibition of the NLRP3 inflammasome.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Inhibition of the NLRP3 inflammasome limits the inflammatory injury following myocardial ischemia-reperfusion in the mouse

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Nlrp3 plays no role in acute cardiac infarction due to low cardiac expression.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Trichothecene mycotoxins activate NLRP3 inflammasome through a P2X7 receptor and Src tyrosine kinase dependent pathway

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Low-dose colchicine for secondary prevention of cardiovascular disease

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Caspase-1 deficiency decreases atherosclerosis in apolipoprotein E-null mice.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5911339

30 November 2018

Identifiers

DOI

10.1155/2018/5702103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29850631%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference