NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis (Q36956703)

17 August 2017

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis (English)

1 reference

17 August 2017

1 reference

1 reference

10

Pål Aukrust

0 references

Geena Paramel Varghese

Geena Paramel Varghese

1

0 references

Mona Skjelland

Mona Skjelland

8

0 references

Kirsten Krohg-Sørensen

Kirsten Krohg-Sørensen

7

0 references

Lasse Folkersen

Lasse Folkersen

2

0 references

Rona J Strawbridge

Rona J Strawbridge

3

0 references

Ulf Hedin

Ulf Hedin

12

0 references

Per Eriksson

Per Eriksson

16

0 references

Terje Espevik

9

Terje Espevik

1 reference

17 August 2017

4

Bente Halvorsen

1 reference

17 August 2017

5

Arne Yndestad

1 reference

17 August 2017

Trine Ranheim

6

1 reference

17 August 2017

Mariette Lengquist

11

1 reference

17 August 2017

Jan-Håkan Jansson

13

1 reference

17 August 2017

Karin Fransén

14

1 reference

17 August 2017

Göran K Hansson

15

1 reference

17 August 2017

Allan Sirsjö

17

1 reference

17 August 2017

20 May 2016

1 reference

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

17 August 2017

1 reference

17 August 2017

5

1 reference

17 August 2017

5

1 reference

P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Myocardial infarction accelerates atherosclerosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Role of NLRP3 and CARD8 in the regulation of TNF-α induced IL-1β release in vascular smooth muscle cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Sensing and reacting to microbes through the inflammasomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Cryopyrin-associated periodic syndrome: an update on diagnosis and treatment response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Endogenous control genes in complex vascular tissue samples

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Population structure in contemporary Sweden--a Y-chromosomal and mitochondrial DNA analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

PLINK: a tool set for whole-genome association and population-based linkage analyses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Cryopyrin activates the inflammasome in response to toxins and ATP

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Gout-associated uric acid crystals activate the NALP3 inflammasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Inflammation in high-grade carotid stenosis: a possible role for macrophages and T cells in plaque destabilization.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

NLRP3 inflammasomes show high expression in aorta of patients with atherosclerosis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Plasma folate and total homocysteine levels are associated with the risk of myocardial infarction, independently of each other and of renal function

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Gender specific associations between matrix metalloproteinases and inflammatory markers in post myocardial infarction patients.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Plasma interleukin (IL)-18 concentrations is elevated in patients with previous myocardial infarction and related to severity of coronary atherosclerosis independently of C-reactive protein and IL-6.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Serum matrix metalloproteinase-3 concentration is influenced by MMP-3 -1612 5A/6A promoter genotype and associated with myocardial infarction.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Expression of interleukin (IL)-18 and functional IL-18 receptor on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for atherogenesis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

A functional interleukin-1 receptor antagonist polymorphism influences atherosclerosis development. The interleukin-1beta:interleukin-1 receptor antagonist balance in atherosclerosis

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Genetic variants inCARD8but not inNLRP3are associated with ankylosing spondylitis

20 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Haemostatic and inflammatory markers are independently associated with myocardial infarction in men and women

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889178

Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury

4 December 2018

1 reference

12 December 2020

Genetic association between NLRP3 variants and Crohn's disease does not replicate in a large UK panel

1 reference

12 December 2020

Interleukin-18/Interleukin-18 Binding Protein Signaling Modulates Atherosclerotic Lesion Development and Stability

1 reference

12 December 2020

Interleukin-1 beta in coronary arteries of patients with ischemic heart disease

1 reference

12 December 2020

The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents

1 reference

12 December 2020

The missense variation Q705K in CIAS1/NALP3/NLRP3 gene and an NLRP1 haplotype are associated with celiac disease

1 reference

12 December 2020

Activated inflammatory cells are associated with plaque rupture in carotid artery stenosis

1 reference

12 December 2020

Genetic variation in proteins of the cryopyrin inflammasome influences susceptibility and severity of rheumatoid arthritis (The Swedish TIRA project)

1 reference

12 December 2020

Lack of Interleukin-1β Decreases the Severity of Atherosclerosis in ApoE-Deficient Mice

1 reference

12 December 2020

ATP induces the release of IL-1 from LPS-primed cells in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1161/JAHA.115.003031

1 reference

17 August 2017

1 reference

17 August 2017

1 reference