SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species (Q104610691)

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scientific article published on 29 December 2020

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English	SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species	scientific article published on 29 December 2020

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33372854%20AND%20SRC:MED&resulttype=core&format=json

1 January 2021

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species (English)

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1 January 2021

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based on heuristic

inferred from title

Papain-like proteinase [SARS-CoV-2]

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based on heuristic

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non-structural protein 5 [SARS-CoV-2]

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based on heuristic

inferred from abstract

SARS-CoV-2 proteases cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species and the search for reservoir hosts

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1 January 2021

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1 January 2021

Alexander N. Freiberg

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Alexander N Freiberg

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1 January 2021

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Mehdi Moustaqil

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1 January 2021

Hsin-Ping Chiu

3

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1 January 2021

Sarah Van Tol

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1 January 2021

Paulina Rudolffi-Soto

5

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1 January 2021

Christian Stevens

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1 January 2021

Akshay Bhumkar

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1 January 2021

Dominic J B Hunter

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1 January 2021

David Jacques

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1 January 2021

Emma Sierecki

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1 January 2021

Yann Gambin

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1 January 2021

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29 December 2020

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1 January 2021

Emerging Microbes & Infections

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1 January 2021

1-27

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1 January 2021

copyright license

Creative Commons Attribution 4.0 International

1 January 2021

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Unexpected instabilities explain batch-to-batch variability in cell-free protein expression systems.

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Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88

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Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

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