Peroxisome proliferator activated receptor gamma (Q1084878)

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mammalian protein found in Homo sapiens
  • peroxisome proliferator-activated receptor-gamma 5
  • PPAR-gamma
  • peroxisome proliferator-activated nuclear receptor gamma variant 1
  • PPARG
  • nuclear receptor subfamily 1 group C member 3
  • peroxisome proliferator-activated receptor gamma
  • peroxisome proliferator-activated receptor-gamma splicing
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Language Label Description Also known as
English
Peroxisome proliferator activated receptor gamma
mammalian protein found in Homo sapiens
  • peroxisome proliferator-activated receptor-gamma 5
  • PPAR-gamma
  • peroxisome proliferator-activated nuclear receptor gamma variant 1
  • PPARG
  • nuclear receptor subfamily 1 group C member 3
  • peroxisome proliferator-activated receptor gamma
  • peroxisome proliferator-activated receptor-gamma splicing

Statements

molecular function
protein binding
determination method
IPI
12 references
retrieved
8 April 2019
stated in
Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors
GOA
curator
UniProt
UniProt protein ID
P37231
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma
GOA
curator
UniProt
UniProt protein ID
P37231
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
Retinoid-dependent recruitment of a histone H1 displacement activity by retinoic acid receptor
GOA
curator
UniProt
UniProt protein ID
P37231
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit
GOA
curator
UniProt
UniProt protein ID
P37231
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism
GOA
curator
UniProt
UniProt protein ID
P37231
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
A comprehensive resource of interacting protein regions for refining human transcription factor networks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
Huntingtin interacting proteins are genetic modifiers of neurodegeneration
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
SIRT1 is regulated by a PPAR{γ}-SIRT1 negative feedback loop associated with senescence
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
retrieved
8 April 2019
stated in
The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IPI
cell component
biological process
positive regulation of transcription by RNA polymerase II
determination method
IDA
IEA
IMP
6 references
retrieved
21 June 2018
stated in
Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231
determination method
IMP
retrieved
21 June 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231
determination method
IEA
retrieved
21 June 2018
stated in
Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma
GOA
curator
UniProt
UniProt protein ID
P37231
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231
determination method
IDA
retrieved
21 June 2018
stated in
PPAR and LXR activators regulate ABCA12 expression in human keratinocytes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231
determination method
IDA
retrieved
21 June 2018
stated in
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231
determination method
IDA
retrieved
21 June 2018
stated in
PPARα and PPARγ activators suppress the monocyte-macrophage apoB-48 receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P37231&geneProductId=UniProtKB:P37231
determination method
IDA
positive regulation of transcription by RNA polymerase II
determination method
IBA
IDA
IEA
IMP
7 references
retrieved
8 April 2019
stated in
Smooth muscle proliferation and role of the prostacyclin (IP) receptor in idiopathic pulmonary arterial hypertension
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IEA
retrieved
8 April 2019
stated in
Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma
GOA
curator
UniProt
UniProt protein ID
P37231
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IDA
retrieved
8 April 2019
stated in
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IDA
retrieved
8 April 2019
stated in
PPAR and LXR activators regulate ABCA12 expression in human keratinocytes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IDA
retrieved
8 April 2019
stated in
PPARα and PPARγ activators suppress the monocyte-macrophage apoB-48 receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37231
determination method
IBA
physically interacts with

Identifiers

Ensembl protein ID
PDB structure ID
 
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