V-rel reticuloendotheliosis viral oncogene homolog A (avian) (Q15326089)

Immunoglobulin-like fold

1 reference

transcription factor RelA (p65)

1 reference

Immunoglobulin E-set

1 reference

Rel homology domain (RHD), DNA-binding domain superfamily

1 reference

IPT domain, protein family

1 reference

Rel homology dimerisation domain, protein family

1 reference

Rel homology domain (RHD), DNA-binding domain, protein family

1 reference

NFkappaB IPT domain, protein family

1 reference

Rel homology domain, conserved site, protein family

1 reference

DNA-binding transcription factor activity

1 reference

12 September 2018

1 reference

12 September 2018

4 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

ankyrin repeat binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

DNA-binding transcription activator activity, RNA polymerase II-specific

IPI

4 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

RNA polymerase II transcription regulatory region sequence-specific DNA binding

3 references

21 June 2018

NF-kappa B and C/EBP transcription factor families synergistically function in mouse serum amyloid A gene expression induced by inflammatory cytokines

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

1 reference

21 June 2018

Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

6 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

34 references

14 February 2019

Core circadian protein CLOCK is a positive regulator of NF-κB-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

The association of Notch2 and NF-kappaB accelerates RANKL-induced osteoclastogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Zbtb7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Lysine 313 of T-box is crucial for modulation of protein stability, DNA binding, and threonine phosphorylation of T-bet

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Zinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-kappaB p65

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

A mutation in NFkB interacting protein 1 results in cardiomyopathy and abnormal skin development in wa3 mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Regulation of the psoriatic chemokine CCL20 by E3 ligases Trim32 and Piasy in keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Two modes of transcriptional activation at native promoters by NF-kappaB p65

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

A fourth IkappaB protein within the NF-kappaB signaling module

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Detection of a ternary complex of NF-kappaB and IkappaBalpha with DNA provides insights into how IkappaBalpha removes NF-kappaB from transcription sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

NF-kappaB dictates the degradation pathway of IkappaBalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Impeding the interaction between Nur77 and p38 reduces LPS-induced inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Regulation of NF-κB activity by competition between RelA acetylation and ubiquitination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Analysis of the RelA:CBP/p300 Interaction Reveals Its Involvement in NF-κB-Driven Transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Bioinformatics and cellular signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13).

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-kappaB.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

IPI

protein kinase binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

13 references

14 February 2019

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

The JNk/NFkappaB pathway is required to activate murine lymphocytes induced by a sulfated polysaccharide from Ecklonia cava

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

α-Actinin 4 potentiates nuclear factor κ-light-chain-enhancer of activated B-cell (NF-κB) activity in podocytes independent of its cytoplasmic actin binding function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

DNA-binding transcription repressor activity, RNA polymerase II-specific

6 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

NF-κB (p65) negatively regulates myocardin-induced cardiomyocyte hypertrophy through multiple mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

NF-κB (p65) negatively regulates myocardin-induced cardiomyocyte hypertrophy through multiple mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

identical protein binding

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Two modes of transcriptional activation at native promoters by NF-kappaB p65

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

sequence-specific DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

A newly identified microRNA, mmu-miR-7578, functions as a negative regulator on inflammatory cytokines tumor necrosis factor-α and interleukin-6 via targeting Egr1 in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

RNA polymerase II transcription regulatory region sequence-specific DNA binding

4 references

14 February 2019

NF-kappa B and C/EBP transcription factor families synergistically function in mouse serum amyloid A gene expression induced by inflammatory cytokines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

DNA-binding transcription factor activity, RNA polymerase II-specific

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Differential regulation of the c-myc oncogene promoter by the NF-kappa B rel family of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

DNA-binding transcription factor activity

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Zbtb7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 references

14 February 2019

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Ablation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

LIME acts as a transmembrane adapter mediating BCR-dependent B-cell activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Argonaute proteins in cardiac tissue contribute to the heart injury during viral myocarditis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

21 June 2018

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

19 references

14 February 2019

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Cutting edge: generation of IL-18 receptor-deficient mice: evidence for IL-1 receptor-related protein as an essential IL-18 binding receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

LIME acts as a transmembrane adapter mediating BCR-dependent B-cell activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

A novel Zinc finger protein, ZCCHC11, interacts with TIFA and modulates TLR signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Angiotensin-(1-7) and the g protein-coupled receptor MAS are key players in renal inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Nucling mediates apoptosis by inhibiting expression of galectin-3 through interference with nuclear factor kappaB signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Argonaute proteins in cardiac tissue contribute to the heart injury during viral myocarditis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

I-kappaB/NF-kappaB complex

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

NF-kappaB p50/p65 complex

3 references

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Peptide-induced negative selection of thymocytes activates transcription of an NF-kappa B inhibitor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

biological process

response to amino acid

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

response to progesterone

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

NIK/NF-kappaB signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

animal organ morphogenesis

1 reference

14 February 2019

NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

response to muscle stretch

1 reference

14 February 2019

Anisotropic regulation of Ankrd2 gene expression in skeletal muscle by mechanical stretch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

negative regulation of protein catabolic process

1 reference

14 February 2019

RelA/p65 regulation of IkappaBbeta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

negative regulation of extrinsic apoptotic signaling pathway

3 references

response to mechanical stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

response to muramyl dipeptide

1 reference

14 February 2019

Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

transcription, DNA-templated

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

positive regulation of transcription, DNA-templated

7 references

14 February 2019

NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Angiopoietin-1 mediates the proangiogenic activity of the bone morphogenic protein antagonist Drm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Differential Regulation of Interleukin (IL)-12 p35 and p40 Gene Expression and Interferon (IFN)-γ–primed IL-12 Production by IFN Regulatory Factor 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

innate immune response

1 reference

21 June 2018

response to cobalamin

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

hair follicle development

1 reference

14 February 2019

NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

cellular response to hepatocyte growth factor stimulus

1 reference

14 February 2019

Hepatocyte growth factor modulates interleukin-6 production in bone marrow derived macrophages: implications for inflammatory mediated diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

acetaldehyde metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

negative regulation of apoptotic process

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

response to lipopolysaccharide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

positive regulation of NF-kappaB transcription factor activity

4 references

14 February 2019

Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

response to inorganic substance

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

regulation of inflammatory response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

response to hydrogen peroxide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

1 reference

14 February 2019

NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1

response to bacterium

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

response to organic cyclic compound

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

cellular response to tumor necrosis factor

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

positive regulation of cell population proliferation

3 references

1 reference

14 February 2019

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

positive regulation of transcription by RNA polymerase II

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

cellular response to hydrogen peroxide

3 references

regulation of transcription, DNA-templated

negative regulation of transcription by RNA polymerase II

ISO

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

NF-κB (p65) negatively regulates myocardin-induced cardiomyocyte hypertrophy through multiple mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

negative regulation of protein sumoylation

1 reference

14 February 2019

NF-κB (p65) negatively regulates myocardin-induced cardiomyocyte hypertrophy through multiple mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

cellular response to lipopolysaccharide

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

Zinc finger protein Gfi1 controls the endotoxin-mediated Toll-like receptor inflammatory response by antagonizing NF-kappaB p65

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

cellular response to vascular endothelial growth factor stimulus

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

negative regulation of pri-miRNA transcription by RNA polymerase II

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q04207&geneProductId=UniProtKB:Q04207

Zbtb7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors.

chromatin organization

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

transcription, DNA-templated

1 reference

14 February 2019

Zbtb7a is a transducer for the control of promoter accessibility by NF-kappa B and multiple other transcription factors.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

I-kappaB kinase/NF-kappaB signaling

inflammatory response

3 references

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04207

Rel homology dimerisation domain

has part(s)

1 reference

IPT domain

1 reference

Rel homology domain (RHD), DNA-binding domain

1 reference

Rel homology domain, conserved site

1 reference

NFkappaB IPT domain

1 reference

Identifiers

1 reference

18 March 2019

1 reference

18 March 2019

1 reference

18 March 2019

1 reference

15 February 2019

1 reference

12 September 2018

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016