The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities (Q28513582)

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Language	Label	Description	Also known as
English	The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities	scientific journal article

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scholarly article

1 reference

25 January 2017

The fatty acid-binding protein, aP2, coordinates macrophage cholesterol trafficking and inflammatory activity. Macrophage expression of aP2 impacts peroxisome proliferator-activated receptor gamma and IkappaB kinase activities (English)

1 reference

25 January 2017

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Inhibitor of nuclear factor kappa-B kinase subunit alpha

1 reference

GOA release 2020-03-11

Inhibitor of kappaB kinase beta

1 reference

GOA release 2020-03-11

Peroxisome proliferator activated receptor gamma

1 reference

GOA release 2020-03-11

Fatty acid binding protein 4, adipocyte

1 reference

GOA release 2020-03-11

V-rel reticuloendotheliosis viral oncogene homolog A (avian)

1 reference

GOA release 2020-03-11

4

object named as

Jill Suttles

1 reference

25 January 2017

Gökhan Hotamışlıgil

5

object named as

Gökhan S. Hotamisligil

1 reference

25 January 2017

1

object named as

Liza Makowski

1 reference

25 January 2017

author name string

Katherine C. Brittingham

2

1 reference

25 January 2017

Joseph M. Reynolds

3

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25 January 2017

language of work or name

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publication date

1 April 2005

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25 January 2017

Journal of Biological Chemistry

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25 January 2017

280

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25 January 2017

13

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25 January 2017

12888–12895

1 reference

25 January 2017

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

19 March 2017

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

19 March 2017

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

19 March 2017

Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

19 March 2017

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

19 March 2017

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

19 March 2017

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

1 reference

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19 March 2017

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

1 reference

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19 March 2017

Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric-oxide synthase by 15-deoxy-Delta12,14-prostaglandin J2

1 reference

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19 March 2017

PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL

1 reference

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19 March 2017

Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma

1 reference

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19 March 2017

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1 reference

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19 March 2017

PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

7 April 2017

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

7 April 2017

Fatty acid binding proteins--the evolutionary crossroads of inflammatory and metabolic responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

Atorvastatin reduces CD68, FABP4, and HBP expression in oxLDL-treated human macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

The adipocyte lipid binding protein (ALBP/aP2) gene facilitates foam cell formation in human THP-1 macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

Adipocyte fatty acid-binding protein, aP2, alters late atherosclerotic lesion formation in severe hypercholesterolemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

CD40-CD40L interactions in atherosclerosis

1 reference

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29 September 2017

Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells

1 reference

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29 September 2017

Troglitazone inhibits atherosclerosis in apolipoprotein E-knockout mice: pleiotropic effects on CD36 expression and HDL.

1 reference

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29 September 2017

Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice

1 reference

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29 September 2017

PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

Improved glucose and lipid metabolism in genetically obese mice lacking aP2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice

1 reference

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29 September 2017

15-deoxy-delta(12,14)-PGJ(2) induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats

1 reference

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29 September 2017

Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

1 reference

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Membrane-bound CD154, but not CD40-specific antibody, mediates NF-kappaB-independent IL-6 production in B cells

1 reference

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29 September 2017

PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

29 September 2017

PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

2 June 2018

The role of PPAR-gamma in macrophage differentiation and cholesterol uptake.

1 reference

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2 June 2018

Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493120

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Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus

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2 June 2018

Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone

1 reference

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27 November 2018

Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662.

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27 November 2018

LPS stimulation of TNF-receptor deficient macrophages: a differential role for TNF-alpha autocrine signaling in the induction of cytokine and nitric oxide production.

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27 November 2018

Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice.

1 reference

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27 November 2018

Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

1 reference

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27 November 2018

Azotemia, TNF alpha, and LPS prime the human neutrophil oxidative burst by distinct mechanisms

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27 November 2018

Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions

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https://pubmed.ncbi.nlm.nih.gov/15684432

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Feedback control of cyclooxygenase-2 expression through PPARgamma

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https://pubmed.ncbi.nlm.nih.gov/15684432

12 December 2020

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Oxidized LDL induces the expression of ALBP/aP2 mRNA and protein in human THP-1 macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/15684432

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