Down-regulation of CTLA-4 by HIV-1 Nef protein (Q21090808)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23372701%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Down-regulation of CTLA-4 by HIV-1 Nef protein (English)

1 reference

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23 February 2020

0 references

3

Nicolas Chomont

Nicolas

Chomont

1 reference

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23 February 2020

9

Rabih Halwani

Rabih

Halwani

1 reference

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23 February 2020

12

Gordon J Freeman

Gordon J

Freeman

1 reference

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23 February 2020

6

Petronela

Ancuta

Petronela Ancuta

1 reference

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23 February 2020

13

Jean-Pierre

Routy

Jean-Pierre Routy

1 reference

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23 February 2020

14

Elias K

Haddad

Elias K Haddad

1 reference

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23 February 2020

15

Rafick-Pierre

Sékaly

Rafick-Pierre Sékaly

1 reference

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23 February 2020

Mohamed El-Far

1

Mohamed

El-Far

1 reference

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23 February 2020

Catherine Isabelle

2

Catherine

Isabelle

1 reference

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23 February 2020

Martin Bourbonnière

4

Martin

Bourbonnière

1 reference

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23 February 2020

Simone Fonseca

5

Simone

Fonseca

1 reference

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23 February 2020

Yoav Peretz

7

Yoav

Peretz

1 reference

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23 February 2020

Younes Chouikh

8

Younes

Chouikh

1 reference

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23 February 2020

Olivier Schwartz

10

Olivier

Schwartz

1 reference

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23 February 2020

Joaquín Madrenas

11

Joaquín

Madrenas

1 reference

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23 February 2020

language of work or name

English

0 references

publication date

23 January 2013

1 reference

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23 February 2020

1 reference

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23 February 2020

volume

8

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23 February 2020

page(s)

e54295

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23 February 2020

issue

1

1 reference

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Creative Commons Attribution 4.0 International

23 February 2020

copyright license

start time

23 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4

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Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein

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Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain

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A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein

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Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

19 March 2017

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A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

19 March 2017

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Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

19 March 2017

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HIV Nef is secreted in exosomes and triggers apoptosis in bystander CD4+ T cells

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes

12 September 2017

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CTLA-4 upregulation during HIV infection: association with anergy and possible target for therapeutic intervention

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4.

12 September 2017

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Beta-COP is essential for transport of protein from the endoplasmic reticulum to the Golgi in vitro

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptors

27 September 2017

1 reference

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HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

27 September 2017

1 reference

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Regulation of cytotoxic T lymphocyte-associated molecule-4 by Src kinases.

27 September 2017

1 reference

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Identification of regions in HIV-1 Nef required for efficient downregulation of cell surface CD4.

27 September 2017

1 reference

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Myristoylation-dependent binding of HIV-1 Nef to CD4.

27 September 2017

1 reference

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Constitutive expression of human immunodeficiency virus (HIV) nef protein in human astrocytes does not influence basal or induced HIV long terminal repeat activity.

27 September 2017

1 reference

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Trafficking of interleukin 2 and transferrin in endosomal fractions of T lymphocytes

27 September 2017

1 reference

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Chloroquine decreases cell-surface expression of tumour necrosis factor receptors in human histiocytic U-937 cells

27 September 2017

1 reference

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Cytotoxic T lymphocyte-associated molecule-4, a high-avidity receptor for CD80 and CD86, contains an intracellular localization motif in its cytoplasmic tail

30 May 2018

1 reference

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Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein

30 May 2018

1 reference

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ARF1 regulates Nef-induced CD4 degradation.

21 January 2018

1 reference

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Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA.

21 January 2018

1 reference

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Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054295

CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054295

Two different forms of human CTLA-4 proteins following peripheral T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054295

Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054295

Human immunodeficiency virus 1 Nef suppresses CD40-dependent immunoglobulin class switching in bystander B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054295

CTLA-4 engagement regulates NF-kappaB activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054295

Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2

21 January 2018

2 references

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0054295

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553160

CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553160

Regulation of surface and intracellular expression of CTLA4 on mouse T cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553160

Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3553160

Interaction between Nef and phosphatidylinositol-3-kinase leads to activation of p21-activated kinase and increased production of HIV

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23372701

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12 December 2020

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Identifiers

DOI

10.1371/JOURNAL.PONE.0054295

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23372701%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

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23 February 2020

1 reference

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