TERF1 interacting nuclear factor 2 (Q21104934)

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mammalian protein found in Homo sapiens
  • TERF1 (TRF1)-interacting nuclear factor 2
  • TERF1-interacting nuclear factor 2
  • TINF2
  • TRF1-interacting nuclear protein 2
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Language Label Description Also known as
English
TERF1 interacting nuclear factor 2
mammalian protein found in Homo sapiens
  • TERF1 (TRF1)-interacting nuclear factor 2
  • TERF1-interacting nuclear factor 2
  • TINF2
  • TRF1-interacting nuclear protein 2

Statements

molecular function
protein binding
determination method
IPI
19 references
retrieved
8 April 2019
stated in
POT1 as a terminal transducer of TRF1 telomere length control
GOA
curator
UniProt
UniProt protein ID
Q9BSI4
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
A human protein-protein interaction network: a resource for annotating the proteome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
The SMC5/6 complex maintains telomere length in ALT cancer cells through SUMOylation of telomere-binding proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
The shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
GNL3L stabilizes the TRF1 complex and promotes mitotic transition
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
PTOP interacts with POT1 and regulates its localization to telomeres
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
retrieved
8 April 2019
stated in
A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BSI4
determination method
IPI
cell component
biological process

Identifiers

Ensembl protein ID
 
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