FKBP prolyl isomerase 8 (Q21110123)

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mammalian protein found in Homo sapiens

FK506-binding protein 8
FKBP-8
38 kDa FKBP
hFKBP38
FKBP-38
38 kDa FK506-binding protein
FKBPR38
FKBP8
rotamase
FK506 binding protein 8, 38kDa
peptidyl-prolyl cis-trans isomerase FKBP8
PPIase FKBP8

Language	Label	Description	Also known as
English	FKBP prolyl isomerase 8	mammalian protein found in Homo sapiens	FK506-binding protein 8 FKBP-8 38 kDa FKBP hFKBP38 FKBP-38 38 kDa FK506-binding protein FKBPR38 FKBP8 rotamase FK506 binding protein 8, 38kDa peptidyl-prolyl cis-trans isomerase FKBP8 PPIase FKBP8

Statements

1 reference

13 November 2019

UniProt protein ID

Tetratricopeptide-like helical domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14318

Peptidyl-prolyl cis-trans isomerase, FKBP-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q14318

Tetratricopeptide repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

based on heuristic

inferred from protein domain or family

Tetratricopeptide repeat family

1 reference

based on heuristic

inferred from protein domain or family

Tetratricopeptide repeat 2 family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14318&geneProductId=UniProtKB:Q14318

determination method

isomerase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

metal ion binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

protein binding

determination method

13 references

9 May 2019

Protrudin induces neurite formation by directional membrane trafficking

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Involvement of FKBP6 in hepatitis C virus replication

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

A single-amino-acid mutation in hepatitis C virus NS5A disrupting FKBP8 interaction impairs viral replication

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Regulation of apoptosis and neurite extension by FKBP38 is required for neural tube formation in the mouse

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Human butyrate-induced transcript 1 interacts with hepatitis C virus NS5A and regulates viral replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

9 May 2019

Involvement of FKBP6 in hepatitis C virus replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

identical protein binding

determination method

1 reference

9 May 2019

Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

disordered domain specific binding

determination method

1 reference

9 May 2019

The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

integral component of membrane

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

mitochondrial membranes

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

integral component of endoplasmic reticulum membrane

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

mitochondrial envelope

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

endoplasmic reticulum

determination method

1 reference

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

determination method

1 reference

9 May 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14318&geneProductId=UniProtKB:Q14318

determination method

protein-containing complex

determination method

1 reference

9 May 2019

The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

biological process

apoptotic process

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

intracellular signal transduction

determination method

1 reference

9 May 2019

muFKBP38: a novel murine immunophilin homolog differentially expressed in Schwannoma cells and central nervous system neurons in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

multicellular organism growth

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

cell fate specification

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

negative regulation of apoptotic process

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

regulation of BMP signaling pathway

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

neural tube development

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

positive regulation of BMP signaling pathway

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

regulation of gene expression

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

smoothened signaling pathway

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

camera-type eye development

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

dorsal/ventral neural tube patterning

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

dorsal/ventral pattern formation

determination method

1 reference

9 May 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

chaperone-mediated protein folding

determination method

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14318&geneProductId=UniProtKB:Q14318

determination method

protein peptidyl-prolyl isomerization

determination method

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

negative regulation of protein phosphorylation

determination method

1 reference

9 May 2019

The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14318

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000222308

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000222308

ENSP00000471700

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000471700

ENSP00000472302

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000472302

ENSP00000476767

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000476767

ENSP00000441267

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000441267

ENSP00000472043

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000472043

ENSP00000472087

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000472087

ENSP00000472643

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000472643

ENSP00000472731

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000472731

ENSP00000472921

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000472921

ENSP00000475588

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475588

ENSP00000475895

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000475895

ENSP00000477278

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000477278

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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