GIT ArfGAP 1 (Q21112695)

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mammalian protein found in Homo sapiens

cool-associated and tyrosine-phosphorylated protein 1
ARF GAP GIT1
GRK-interacting protein 1
GIT1
CAT1
G protein-coupled receptor kinase-interactor 1
CAT-1
ARF GTPase-activating protein GIT1
G protein-coupled receptor kinase interacting ArfGAP 1

Language	Label	Description	Also known as
English	GIT ArfGAP 1	mammalian protein found in Homo sapiens	cool-associated and tyrosine-phosphorylated protein 1 ARF GAP GIT1 GRK-interacting protein 1 GIT1 CAT1 G protein-coupled receptor kinase-interactor 1 CAT-1 ARF GTPase-activating protein GIT1 G protein-coupled receptor kinase interacting ArfGAP 1

Statements

1 reference

13 November 2019

UniProt protein ID

ARFGAP/RecO-like zinc finger

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2X7

Ankyrin repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2X7

ArfGAP domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2X7

Arf GTPase activating protein family

1 reference

based on heuristic

inferred from protein domain or family

Arf GTPase-activating protein GIT1/2, coiled-coil domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

GIT, Spa2 homology (SHD) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

ARF GTPase-activating protein GIT1, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

11 references

8 April 2019

The serologically defined colon cancer antigen-3 interacts with the protein tyrosine phosphatase PTPN13 and is involved in the regulation of cytokinesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

Mammalian Scribble forms a tight complex with the betaPIX exchange factor

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

betaPIX controls cell motility and neurite extension by regulating the distribution of GIT1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

GIT2 represses Crk- and Rac1-regulated cell spreading and Cdc42-mediated focal adhesion turnover

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

G protein-coupled receptor kinase 2 positively regulates epithelial cell migration

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

N-α-acetyltransferase 10 protein suppresses cancer cell metastasis by binding PIX proteins and inhibiting Cdc42/Rac1 activity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

determination method

1 reference

26 September 2017

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2X7&geneProductId=UniProtKB:Q9Y2X7

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

determination method

1 reference

8 April 2019

Defining the membrane proteome of NK cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

biological process

positive regulation of GTPase activity

determination method

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

regulation of cytokinesis

determination method

1 reference

8 April 2019

The serologically defined colon cancer antigen-3 interacts with the protein tyrosine phosphatase PTPN13 and is involved in the regulation of cytokinesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

regulation of G protein-coupled receptor signaling pathway

determination method

1 reference

8 April 2019

beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

presynaptic modulation of chemical synaptic transmission

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

regulation of synaptic vesicle exocytosis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2X7

determination method

Arf GTPase-activating protein GIT1/2, coiled-coil domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2X7

GIT, Spa2 homology (SHD) domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2X7

ankyrin repeat-containing domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2X7

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2X7

ARF GTPase-activating protein GIT1, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2X7

Arf GTPase activating protein

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2X7

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000225394

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000225394

ENSP00000378338

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000378338

ENSP00000334125

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000334125

ENSP00000462775

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000462775

ENSP00000463435

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463435

ENSP00000463543

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463543

ENSP00000463746

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000463746

ENSP00000464388

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464388

ENSP00000464933

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000464933

ENSP00000466824

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000466824

0 references

Sitelinks

Wikipedia(4 entries)

dewiki ARF-GTPase-aktivierendes Protein 1
enwiki GIT1
ttwiki GIT1
ukwiki GIT1

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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