Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma (Q24319145)

Rho guanine nucleotide exchange factor 7

1 reference

activation of GTPase activity

1 reference

Scribbled planar cell polarity

1 reference

Aron B Jaffe

6

0 references

Avi Rosenberg

object named as

Avi Rosenberg

2

0 references

author name string

Lixing Zhan

1

0 references

Kenneth C Bergami

3

0 references

Min Yu

4

0 references

Zhenyu Xuan

5

0 references

Craig Allred

7

0 references

Senthil K Muthuswamy

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin

8

0 references

language of work or name

English

0 references

publication date

28 November 2008

0 references

published in

Cell

0 references

volume

135

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page(s)

865-78

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issue

5

0 references

cites work

1 reference

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Mammalian Scribble forms a tight complex with the betaPIX exchange factor

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Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence

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Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

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Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

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Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration

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27 September 2017

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27 September 2017

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27 September 2017

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Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble

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Adaptation of core mechanisms to generate cell polarity

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27 September 2017

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27 September 2017

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27 September 2017

1 reference

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27 September 2017

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27 September 2017

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Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription

27 September 2017

1 reference

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27 September 2017

1 reference

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27 September 2017

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27 September 2017

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27 September 2017

1 reference

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Organization of mammary epithelial cells into 3D acinar structures requires glucocorticoid and JNK signaling.

27 September 2017

1 reference

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Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice.

30 May 2018

1 reference

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30 May 2018

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Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion

30 May 2018

1 reference

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Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

30 May 2018

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29 November 2018

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29 November 2018

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29 November 2018

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29 November 2018

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Cultured mouse mammary epithelial cells: normal phenotype after implantation

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Crossref

https://api.crossref.org/works/10.1016%2FJ.CELL.2008.09.045

7 January 2021

inferred from DOI database lookup

Cooperation of TGF alpha and c-Myc in mouse mammary tumorigenesis: coordinated stimulation of growth and suppression of apoptosis

1 reference

12 December 2020

10.1016/J.CELL.2008.09.045

Identifiers

DOI

1 reference

1790759

1790759

1 reference

1 reference

1 reference