Thyroid hormone receptor associated protein 3 (Q21116038)

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mammalian protein found in Homo sapiens

BCLAF1 and THRAP3 family member 2
thyroid hormone receptor-associated protein, 150 kDa subunit
thyroid hormone receptor-associated protein 3
Trap150
thyroid hormone receptor-associated protein complex 150 kDa component
THRAP3
TR-associated protein, 150-kDa

Language	Label	Description	Also known as
English	Thyroid hormone receptor associated protein 3	mammalian protein found in Homo sapiens	BCLAF1 and THRAP3 family member 2 thyroid hormone receptor-associated protein, 150 kDa subunit thyroid hormone receptor-associated protein 3 Trap150 thyroid hormone receptor-associated protein complex 150 kDa component THRAP3 TR-associated protein, 150-kDa

Statements

1 reference

13 November 2019

UniProt protein ID

Thyroid hormone receptor-associated protein 3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Y2W1

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

transcription coactivator activity

determination method

3 references

8 April 2019

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

transcription coregulator activity

determination method

3 references

26 September 2017

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2W1&geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

thyroid hormone receptor binding

determination method

1 reference

8 April 2019

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

phosphoprotein binding

determination method

1 reference

8 April 2019

Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

protein binding

determination method

6 references

8 April 2019

The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Regulation of cyclin D1 RNA stability by SNIP1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

nuclear receptor coactivator activity

determination method

1 reference

1 January 2018

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2W1&geneProductId=UniProtKB:Q9Y2W1

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

vitamin D receptor binding

determination method

1 reference

8 April 2019

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

signaling receptor activity

determination method

1 reference

1 January 2018

A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2W1&geneProductId=UniProtKB:Q9Y2W1

determination method

nuclear receptor coactivator activity

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

mediator complex

determination method

3 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

exon-exon junction complex

determination method

1 reference

8 April 2019

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

extracellular exosome

determination method

1 reference

26 September 2017

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2W1&geneProductId=UniProtKB:Q9Y2W1

determination method

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

Composite co-activator ARC mediates chromatin-directed transcriptional activation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

8 April 2019

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

extracellular exosome

determination method

1 reference

8 April 2019

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

biological process

androgen receptor signaling pathway

determination method

1 reference

1 January 2018

A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2W1&geneProductId=UniProtKB:Q9Y2W1

determination method

regulation of transcription, DNA-templated

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2W1&geneProductId=UniProtKB:Q9Y2W1

determination method

positive regulation of mRNA splicing, via spliceosome

determination method

1 reference

8 April 2019

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

rhythmic process

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

mRNA processing

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

intracellular steroid hormone receptor signaling pathway

determination method

1 reference

1 January 2018

The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2W1&geneProductId=UniProtKB:Q9Y2W1

determination method

regulation of alternative mRNA splicing, via spliceosome

determination method

1 reference

8 April 2019

Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

transcription, DNA-templated

determination method

1 reference

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y2W1&geneProductId=UniProtKB:Q9Y2W1

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

nuclear-transcribed mRNA catabolic process

determination method

1 reference

8 April 2019

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

mRNA stabilization

determination method

1 reference

8 April 2019

Regulation of cyclin D1 RNA stability by SNIP1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

circadian rhythm

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

determination method

2 references

positive regulation of circadian rhythm

determination method

1 reference

8 April 2019

A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

transcription initiation from RNA polymerase II promoter

determination method

1 reference

8 April 2019

A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

positive regulation of transcription by RNA polymerase II

determination method

1 reference

8 April 2019

Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y2W1

determination method

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000346634

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000346634

ENSP00000433825

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000433825

ENSP00000498001

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000498001

Sitelinks

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Multilingual sites(0 entries)

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