The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus (Q24301338)

3

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Melissa J. Moore

7

object named as

Melissa J Moore

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author name string

Guramrit Singh

1

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John D Leszyk

4

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Scott A Shaffer

5

0 references

Zhiping Weng

Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly

6

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language of work or name

English

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publication date

9 November 2012

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published in

Cell

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volume

151

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page(s)

750-64

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issue

4

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Genome analysis reveals interplay between 5'UTR introns and nuclear mRNA export for secretory and mitochondrial genes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

SON controls cell-cycle progression by coordinated regulation of RNA splicing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Human mRNA export machinery recruited to the 5' end of mRNA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Splicing enhances translation in mammalian cells: an additional function of the exon junction complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Evidence for reassociation of RNA-binding proteins after cell lysis: implications for the interpretation of immunoprecipitation analyses

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The SR protein family of splicing factors: master regulators of gene expression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

From birth to death: the complex lives of eukaryotic mRNAs

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Messenger-RNA-binding proteins and the messages they carry

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Intrinsic disorder in the human spliceosomal proteome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Assembly, disassembly and recycling: the dynamics of exon junction complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The exon junction complex differentially marks spliced junctions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Genome-wide identification of alternative splice forms down-regulated by nonsense-mediated mRNA decay in Drosophila

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Execution of nonsense-mediated mRNA decay: what defines a substrate?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Specific combinations of SR proteins associate with single pre-messenger RNAs in vivo and contribute different functions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Alternative splicing resulting in nonsense-mediated mRNA decay: what is the meaning of nonsense?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Regulation of multiple core spliceosomal proteins by alternative splicing-coupled nonsense-mediated mRNA decay

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The splicing factor SF2/ASF regulates translation initiation by enhancing phosphorylation of 4E-BP1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Efficiency of the pioneer round of translation affects the cellular site of nonsense-mediated mRNA decay

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Introns play an essential role in splicing-dependent formation of the exon junction complex.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The nuclear nurture and cytoplasmic nature of localized mRNPs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Compensatory relationship between splice sites and exonic splicing signals depending on the length of vertebrate introns

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Building specificity with nonspecific RNA-binding proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

SRprises along a messenger's journey

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

The ever-increasing complexities of the exon junction complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

eIF4AIII binds spliced mRNA in the exon junction complex and is essential for nonsense-mediated decay

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Exon junction complexes mediate the enhancing effect of splicing on mRNA expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Flexibility in the site of exon junction complex deposition revealed by functional group and RNA secondary structure alterations in the splicing substrate

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

CWC22 connects pre-mRNA splicing and exon junction complex assembly.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Purification of nuclear poly(A)-binding protein Nab2 reveals association with the yeast transcriptome and a messenger ribonucleoprotein core structure

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Visualization of the formation and transport of a specific hnRNP particle.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3522173

Involvement of SR proteins in mRNA surveillance

30 May 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23084401

12 December 2020

inferred from PubMed ID database lookup

RNA splicing promotes translation and RNA surveillance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23084401

12 December 2020

inferred from PubMed ID database lookup

The three-dimensional arcitecture of the EJC core

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23084401

12 December 2020

inferred from PubMed ID database lookup

Scaffold: a bioinformatic tool for validating MS/MS-based proteomic studies

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

UNAFold: software for nucleic acid folding and hybridization

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Deep proteome and transcriptome mapping of a human cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Alternative isoform regulation in human tissue transcriptomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Global quantification of mammalian gene expression control

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Mapping and quantifying mammalian transcriptomes by RNA-Seq

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Informatics platform for global proteomic profiling and biomarker discovery using liquid chromatography-tandem mass spectrometry.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Next generation software for functional trend analysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

BEDTools: a flexible suite of utilities for comparing genomic features

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Detection of nonneutral substitution rates on mammalian phylogenies

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Quantitative evaluation of all hexamers as exonic splicing elements

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

WebLogo: A Sequence Logo Generator

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Predictive identification of exonic splicing enhancers in human genes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Distinct RNP complexes of shuttling hnRNP proteins with pre-mRNA and mRNA: candidate intermediates in formation and export of mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

From RNA-seq reads to differential expression results

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2012.10.007

7 January 2021

10.1016/J.CELL.2012.10.007

Identifiers

DOI

1 reference

3226830

3226830

1 reference

1 reference

1 reference