Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence (Q24293467)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22002537%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22002537%20AND%20SRC:MED&resulttype=core&format=json

T-box transcription factor 2

14 January 2020

main subject

1 reference

PML nuclear body scaffold

1 reference

T-box transcription factor 3

1 reference

cellular senescence

1 reference

author

Nadine Martin

1

1 reference

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14 January 2020

author name string

Moussa Benhamed

2

1 reference

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14 January 2020

Karim Nacerddine

3

1 reference

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14 January 2020

Maud D Demarque

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22002537%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Maarten van Lohuizen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22002537%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

Anne Dejean

6

1 reference

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14 January 2020

Oliver Bischof

7

1 reference

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14 January 2020

language of work or name

English

0 references

publication date

14 October 2011

1 reference

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14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22002537%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

volume

31

1 reference

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14 January 2020

issue

1

1 reference

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14 January 2020

page(s)

95-109

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Role of the polycomb repressive complex 2 in acute promyelocytic leukemia

14 January 2020

cites work

1 reference

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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

19 March 2017

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PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

19 March 2017

1 reference

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Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression

19 March 2017

1 reference

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Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

19 March 2017

1 reference

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

19 March 2017

1 reference

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The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis

19 March 2017

1 reference

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A common set of gene regulatory networks links metabolism and growth inhibition

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

PML protein isoforms and the RBCC/TRIM motif

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

The transcriptional role of PML and the nuclear body

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

The regulation of E2F by pRB-family proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

PML is a direct p53 target that modulates p53 effector functions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Role of PML in cell growth and the retinoic acid pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Cellular senescence: when bad things happen to good cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Sibling rivalry in the E2F family

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Regulation of E2Fs and senescence by PML nuclear bodies.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

The T-box transcription factor Tbx2: its role in development and possible implication in cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Expression of TBX2 promotes anchorage-independent growth and survival in the p53-negative SW13 adrenocortical carcinoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Heat shock protein Hsp72 controls oncogene-induced senescence pathways in cancer cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Ectopic Tbx2 expression results in polyploidy and cisplatin resistance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

A role for Tbx2 in the regulation of the alpha2(1) collagen gene in human fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

PML and PML nuclear bodies: implications in antiviral defence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Transcriptional regulation is affected by subnuclear targeting of reporter plasmids to PML nuclear bodies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Regulation of cellular senescence by Rb2/p130.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Human papillomavirus oncoprotein E7 targets the promyelocytic leukemia protein and circumvents cellular senescence via the Rb and p53 tumor suppressor pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Molecular mechanisms of E2F-dependent activation and pRB-mediated repression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Loss of the tumor suppressor PML in human cancers of multiple histologic origins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Promyelocytic leukemia nuclear bodies associate with transcriptionally active genomic regions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Deconstructing PML-induced premature senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Histone deacetylases: a common molecular target for differentiation treatment of acute myeloid leukemias?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

The biology of acute promyelocytic leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

PML is induced by oncogenic ras and promotes premature senescence

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Conservation of the T-box gene family from Mus musculus to Caenorhabditis elegans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

Primary and compensatory roles for RB family members at cell cycle gene promoters that are deacetylated and downregulated in doxorubicin-induced senescence of breast cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

A negative feedback signaling network underlies oncogene-induced senescence

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.370

Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.370

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.370

The epigenetic magic of histone lysine methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.370

Human fibroblasts require the Rb family of tumor suppressors, but not p53, for PML-induced senescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.370

Atmospheric carbon dioxide concentrations over the past 60 million years

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2011.370

Inducible activation of Ras and Raf in adult epidermis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252579

29 November 2018

Identifiers

DOI

10.1038/EMBOJ.2011.370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22002537%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22002537%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

22002537

1 reference