Insulin receptor substrate 2 (Q21173765)

IBA

14-3-3 protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

5 references

8 April 2019

Insulin receptor substrate-2 is expressed in kidney epithelium and up-regulated in diabetic nephropathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

Phosphoinositide 3-kinase as a novel functional target for the regulation of the insulin signaling pathway by SIRT1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

IPI

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4H2&geneProductId=UniProtKB:Q9Y4H2

1-phosphatidylinositol-3-kinase activity

1 reference

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4H2&geneProductId=UniProtKB:Q9Y4H2

signal transducer activity

4 references

24 April 2018

Role of IRS-2 in insulin and cytokine signalling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4H2&geneProductId=UniProtKB:Q9Y4H2

24 April 2018

Disruption of IRS-2 causes type 2 diabetes in mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4H2&geneProductId=UniProtKB:Q9Y4H2

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4H2&geneProductId=UniProtKB:Q9Y4H2

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4H2&geneProductId=UniProtKB:Q9Y4H2

protein phosphatase binding

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

protein domain specific binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

positive regulation of fatty acid beta-oxidation

biological process

1 reference

8 April 2019

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

positive regulation of glucose import

IMP

1 reference

8 April 2019

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

positive regulation of glycogen biosynthetic process

IMP

cellular response to peptide

NAS

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

positive regulation of cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

positive regulation of glucose metabolic process

1 reference

8 April 2019

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

mammary gland development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

regulation of lipid metabolic process

1 reference

8 April 2019

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

negative regulation of long-chain fatty acid import across plasma membrane

1 reference

8 April 2019

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

positive regulation of mesenchymal cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

1 reference

8 April 2019

siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

glucose metabolic process

1 reference

8 April 2019

Disruption of IRS-2 causes type 2 diabetes in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

cell population proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

phosphatidylinositol-mediated signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

cellular response to glucose stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

phosphatidylinositol-3-phosphate biosynthetic process

1 reference

7 November 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4H2&geneProductId=UniProtKB:Q9Y4H2

phosphatidylinositol phosphate biosynthetic process

1 reference

7 November 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4H2&geneProductId=UniProtKB:Q9Y4H2

insulin receptor signaling pathway

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

interleukin-7-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

positive regulation of protein kinase B signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2

positive regulation of Ras protein signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4H2