Patched 1 (Q21989959)

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mammalian protein found in Mus musculus
  • patched homolog 1
  • mesenchymal dysplasia
  • Ptch1
  • Ptch1 protein +12b
  • protein patched homolog 1
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Language Label Description Also known as
English
Patched 1
mammalian protein found in Mus musculus
  • patched homolog 1
  • mesenchymal dysplasia
  • Ptch1
  • Ptch1 protein +12b
  • protein patched homolog 1

Statements

molecular function
protein binding
determination method
IPI
6 references
stated in
UniProt
UniProt protein ID
Q61115
retrieved
9 August 2016
language of work or name
English
retrieved
9 May 2019
stated in
Sonic hedgehog protein signals not as a hydrolytic enzyme but as an apparent ligand for patched
GOA
curator
UniProt
UniProt protein ID
Q61115
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IPI
retrieved
9 May 2019
stated in
Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels
GOA
curator
UniProt
UniProt protein ID
Q61115
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IPI
retrieved
9 May 2019
stated in
Disruption of Scube2 Impairs Endochondral Bone Formation
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IPI
retrieved
9 May 2019
stated in
Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IPI
retrieved
9 May 2019
stated in
Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IPI
cell component
plasma membrane
determination method
IBA
IDA
IEA
ISO
TAS
8 references
retrieved
9 May 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
TAS
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
ISO
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q61115
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IEA
retrieved
9 May 2019
stated in
Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IDA
retrieved
9 May 2019
stated in
Patched1 interacts with cyclin B1 to regulate cell cycle progression
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IDA
retrieved
9 May 2019
stated in
The hedgehog receptor patched is involved in cholesterol transport
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IBA
biological process
smoothened signaling pathway
determination method
IBA
IDA
IEA
IGI
IMP
7 references
retrieved
9 May 2019
stated in
GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IMP
retrieved
9 May 2019
stated in
A spontaneous mouse mutation, mesenchymal dysplasia (mes), is caused by a deletion of the most C-terminal cytoplasmic domain of patched (ptc)
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IMP
retrieved
9 May 2019
stated in
C2cd3 is required for cilia formation and Hedgehog signaling in mouse.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IGI
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IEA
retrieved
9 May 2019
stated in
Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IDA
retrieved
9 May 2019
stated in
Haploinsufficiency of the forkhead gene Foxf1, a target for sonic hedgehog signaling, causes lung and foregut malformations
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61115
determination method
IBA

Identifiers

 
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