Disruption of Scube2 Impairs Endochondral Bone Formation (Q28591452)

31 January 2017

title

Disruption of Scube2 Impairs Endochondral Bone Formation (English)

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31 January 2017

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Signal peptide, CUB domain, EGF-like 3

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Signal peptide, CUB domain, EGF-like 2

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Patched 1

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Signal peptide, CUB domain, EGF-like 1

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Sonic hedgehog

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Desert hedgehog

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Ruey-Bing Yang

4

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author name string

Yuh-Charn Lin

series ordinal

1

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31 January 2017

Steve R. Roffler

series ordinal

2

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31 January 2017

Yu-Ting Yan

series ordinal

3

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31 January 2017

publication date

1 July 2015

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Journal of Bone and Mineral Research

31 January 2017

published in

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31 January 2017

volume

30

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31 January 2017

issue

7

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31 January 2017

page(s)

1255–1267

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Isolation and characterization of a secreted, cell-surface glycoprotein SCUBE2 from humans

31 January 2017

cites work

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Identification of a novel family of cell-surface proteins expressed in human vascular endothelium

21 January 2018

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Domain and functional analysis of a novel breast tumor suppressor protein, SCUBE2

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Tumor suppressor SCUBE2 inhibits breast-cancer cell migration and invasion through the reversal of epithelial-mesenchymal transition

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Structure and function of the serine-protease subcomponents of C1: protein engineering studies

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Cloning, mapping, and expression analysis of a gene encoding a novel mammalian EGF-related protein (SCUBE1).

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The you gene encodes an EGF-CUB protein essential for Hedgehog signaling in zebrafish

21 January 2018

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The zebrafish-secreted matrix protein you/scube2 is implicated in long-range regulation of hedgehog signaling.

21 January 2018

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Scube2 mediates Hedgehog signalling in the zebrafish embryo

21 January 2018

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A novel secreted, cell-surface glycoprotein containing multiple epidermal growth factor-like repeats and one CUB domain is highly expressed in primary osteoblasts and bones

21 January 2018

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Scube2 expression extends beyond the central nervous system during mouse development.

21 January 2018

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The role of the perichondrium in fetal bone development

21 January 2018

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Distinguishing the contributions of the perichondrium, cartilage, and vascular endothelium to skeletal development.

21 January 2018

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Developmental roles and clinical significance of hedgehog signaling

21 January 2018

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Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

21 January 2018

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Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development

21 January 2018

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Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton

21 January 2018

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Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy

21 January 2018

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Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone

21 January 2018

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Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form

21 January 2018

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Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand

21 January 2018

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Scube2 enhances proteolytic Shh processing from the surface of Shh-producing cells

21 January 2018

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Indian hedgehog: its roles and regulation in endochondral bone development

21 January 2018

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

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Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease

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Genome-scale loss-of-function screening with a lentiviral RNAi library

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Core-binding factor alpha 1 (Cbfa1) induces osteoblastic differentiation of C2C12 cells without interactions with Smad1 and Smad5.

21 January 2018

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Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

21 January 2018

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Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S.

21 January 2018

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Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function

21 January 2018

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Induction of osteogenic differentiation by hedgehog proteins.

21 January 2018

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Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh.

21 January 2018

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Sonic hedgehog shedding results in functional activation of the solubilized protein.

21 January 2018

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Heparan sulfate-modulated, metalloprotease-mediated sonic hedgehog release from producing cells

21 January 2018

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Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

21 January 2018

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Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.

21 January 2018

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High expression and anterograde axonal transport of aminoterminal sonic hedgehog in the adult hamster brain

21 January 2018

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Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JBMR.2451

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017