Recombination signal binding protein for immunoglobulin kappa J region (Q21990370)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

DNA-binding transcription factor activity

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

transcription factor binding

3 references

transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

3 references

14 February 2019

Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

7 references

14 February 2019

p48 subunit of mouse PTF1 binds to RBP-Jkappa/CBF-1, the intracellular mediator of Notch signalling, and is expressed in the neural tube of early stage embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

RBP-L, a transcription factor related to RBP-Jkappa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Structure and Function of the CSL-KyoT2 Corepressor Complex: A Negative Regulator of Notch Signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch1 regulates the fate of cardiac progenitor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Pten coordinates retinal neurogenesis by regulating Notch signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

sequence-specific DNA binding

IPI

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Notch directly regulates Gata3 expression during T helper 2 cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

4 references

14 February 2019

HERP1 is a cell type-specific primary target of Notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

RBP-L, a transcription factor related to RBP-Jkappa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

RNA polymerase II cis-regulatory region sequence-specific DNA binding

IDA

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

protein-containing complex binding

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

DNA-binding transcription activator activity, RNA polymerase II-specific

6 references

1 January 2018

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

1 January 2018

Notch signaling regulates left-right asymmetry determination by inducing Nodal expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

1 January 2018

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

sequence-specific DNA binding

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch directly regulates Gata3 expression during T helper 2 cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

DNA-binding transcription activator activity, RNA polymerase II-specific

5 references

14 February 2019

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch signaling regulates left-right asymmetry determination by inducing Nodal expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

transcription regulator complex

1 reference

5 June 2018

Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

3 references

9 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

HERP1 is a cell type-specific primary target of Notch

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Canonical notch signaling functions as a commitment switch in the epidermal lineage

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Conservation of the Notch signalling pathway in mammalian neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

RBP-L, a transcription factor related to RBP-Jkappa

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

protein-containing complex

IC

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

MAML1-RBP-Jkappa- ICN1 complex

3 references

10 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

HERP1 is a cell type-specific primary target of Notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Canonical notch signaling functions as a commitment switch in the epidermal lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Conservation of the Notch signalling pathway in mammalian neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

RBP-L, a transcription factor related to RBP-Jkappa

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

dorsal aorta morphogenesis

biological process

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

epithelial to mesenchymal transition involved in endocardial cushion formation

1 reference

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

regulation of transcription by RNA polymerase II

1 reference

5 June 2018

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

positive regulation of Notch signaling pathway involved in heart induction

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

outflow tract morphogenesis

TAS

1 reference

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of cell proliferation involved in heart morphogenesis

1 reference

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

arterial endothelial cell fate commitment

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

endocardium morphogenesis

1 reference

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

negative regulation of ossification

1 reference

14 February 2019

Diet-induced aortic valve disease in mice haploinsufficient for the Notch pathway effector RBPJK/CSL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

TAS

blood vessel remodeling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of cardiac muscle cell proliferation

1 reference

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

humoral immune response

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells

B cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Notch signaling pathway involved in arterial endothelial cell fate commitment

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

negative regulation of cell population proliferation

IC

1 reference

14 February 2019

Canonical notch signaling functions as a commitment switch in the epidermal lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

club cell differentiation

1 reference

14 February 2019

Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

1 reference

14 February 2019

Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

atrioventricular canal development

1 reference

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment

1 reference

14 February 2019

Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

epidermal cell fate specification

1 reference

14 February 2019

Canonical notch signaling functions as a commitment switch in the epidermal lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

cardiac left ventricle morphogenesis

1 reference

14 February 2019

Diet-induced aortic valve disease in mice haploinsufficient for the Notch pathway effector RBPJK/CSL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

labyrinthine layer blood vessel development

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

transcription, DNA-templated

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

1 reference

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

defense response to bacterium

1 reference

14 February 2019

Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

sebaceous gland development

1 reference

14 February 2019

Canonical notch signaling functions as a commitment switch in the epidermal lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

1 reference

14 February 2019

Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

inflammatory response to antigenic stimulus

1 reference

14 February 2019

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

regulation of timing of cell differentiation

1 reference

14 February 2019

Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

negative regulation of transcription by RNA polymerase II

5 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

blood vessel lumenization

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

ventricular trabecula myocardium morphogenesis

1 reference

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of transcription of Notch receptor target

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch-regulated ankyrin-repeat protein inhibits Notch1 signaling: multiple Notch1 signaling pathways involved in T cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Conservation of the Notch signalling pathway in mammalian neurogenesis

neuron differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

epithelial to mesenchymal transition

1 reference

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of BMP signaling pathway

1 reference

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

regulation of gene expression

1 reference

14 February 2019

Conservation of the Notch signalling pathway in mammalian neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of ERBB signaling pathway

1 reference

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

negative regulation of transcription, DNA-templated

regulation of cell adhesion involved in heart morphogenesis

1 reference

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

pituitary gland development

IC

1 reference

14 February 2019

Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

determination of heart left/right asymmetry

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

somatic stem cell population maintenance

TAS

1 reference

14 February 2019

Notch signaling in stomach epithelial stem cell homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Canonical notch signaling functions as a commitment switch in the epidermal lineage

hair follicle maturation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of ephrin receptor signaling pathway

1 reference

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

myeloid dendritic cell differentiation

1 reference

14 February 2019

Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

keratinocyte differentiation

1 reference

14 February 2019

Canonical notch signaling functions as a commitment switch in the epidermal lineage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Notch signaling is essential for ventricular chamber development

endocardium development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

auditory receptor cell fate commitment

1 reference

14 February 2019

Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of gene expression

3 references

14 February 2019

Transcriptome analysis for Notch3 target genes identifies Grip2 as a novel regulator of myogenic response in the cerebrovasculature

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch-Tnf signalling is required for development and homeostasis of arterial valves.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

regulation of cell population proliferation

1 reference

14 February 2019

RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of cell population proliferation

1 reference

14 February 2019

Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of transcription from RNA polymerase II promoter in response to hypoxia

3 references

blood vessel endothelial cell fate specification

1 reference

14 February 2019

Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of transcription by RNA polymerase II

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Monitoring Notch1 activity in development: evidence for a feedback regulatory loop

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch signaling regulates left-right asymmetry determination by inducing Nodal expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

transcription by RNA polymerase II

IDA

1 reference

5 June 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

HERP1 is a cell type-specific primary target of Notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Notch signaling pathway

8 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31266&geneProductId=UniProtKB:P31266

1 reference

14 February 2019

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

negative regulation of neuron projection development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

negative regulation of smooth muscle cell migration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

negative regulation of smooth muscle cell apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

positive regulation of smooth muscle cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Notch-Tnf signalling is required for development and homeostasis of arterial valves.

aortic valve development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

pulmonary valve development

1 reference

14 February 2019

Notch-Tnf signalling is required for development and homeostasis of arterial valves.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

ventricular septum morphogenesis

1 reference

14 February 2019

Notch-Tnf signalling is required for development and homeostasis of arterial valves.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

negative regulation of transcription by RNA polymerase II

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch signaling is essential for ventricular chamber development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

Notch signaling pathway

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

RBPJ in mouse Sertoli cells is required for proper regulation of the testis stem cell niche

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266

negative regulation of cold-induced thermogenesis

1 reference

14 February 2019

Inhibition of Notch signaling promotes browning of white adipose tissue and ameliorates obesity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31266